Mog Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mog
myelin oligodendrocyte glycoprotein
MGI:97435

26 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fadd^tm1Mpa/Fadd^tm1Mpa Mog^tm1(cre)Gkl/Mog⁺ involves: C57BL/6 * SJL	abnormal oligodendrocyte apoptosis	J:167475
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:167475
	normal immune system phenotype	J:167475
	normal nervous system phenotype	J:167475
Fas^tm1Cgn/Fas^tm1Cgn Mog^tm1(cre)Gkl/Mog⁺ involves: C57BL/6	decreased susceptibility to experimental autoimmune encephalomyelitis	J:114741
	normal immune system phenotype	J:114741
Fas^tm1Cgn/Fas^tm1Cgn Mog^tm1(cre)Gkl/Mog⁺ Tnfrsf1a^tm1Mak/Tnfrsf1a^tm1Mak involves: 129S2/SvPas * C57BL/6	decreased susceptibility to experimental autoimmune encephalomyelitis	J:114741
	normal immune system phenotype	J:114741
Gt(ROSA)26Sor^tm1(HA)Libl/Gt(ROSA)26Sor^tm1(HA)Libl Mog^tm1(cre)Gkl/? involves: 129/Sv * C57BL/6	normal behavior/neurological phenotype	J:137838
	normal immune system phenotype	J:137838
Gt(ROSA)26Sor^tm1(HA)Libl/Gt(ROSA)26Sor^tm1(HA)Libl Mog^tm1(cre)Gkl/? Tg(TcraCl4,TcrbCl4)1Shrm/0 involves: 129/Sv * BALB/c * C57BL/6	abnormal oligodendrocyte morphology	J:137838
	abnormal optic nerve morphology	J:137838
	brain inflammation	J:137838
	decreased locomotor activity	J:137838
	demyelination	J:137838
	impaired righting response	J:137838
	optic nerve inflammation	J:137838
	spinal cord inflammation	J:137838
	tremors	J:137838
	weight loss	J:137838
Gt(ROSA)26Sor^{tm1(HBEGF)Awai}/Gt(ROSA)26Sor^{tm1(HBEGF)Awai} Mog^tm1(cre)Gkl/? involves: C57BL/6	abnormal immune system physiology	J:131076
	abnormal neuron morphology	J:131076
	astrocytosis	J:131076
	demyelination	J:131076
	hindlimb paralysis	J:131076
	increased neuron apoptosis	J:131076
	tremors	J:131076
	weight loss	J:131076
Igh-J^tm1Aigl/Igh-J⁺ Mog^tm1Dpd/Mog^tm1Dpd Tg(Tcra2D2,Tcrb2D2)1Kuch/0 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal nervous system morphology	J:151335
	abnormal optic nerve morphology	J:151335
	abnormal spinal cord morphology	J:151335
	CNS inflammation	J:151335
	demyelination	J:151335
	increased susceptibility to experimental autoimmune encephalomyelitis	J:151335
	muscle hypertonia	J:151335
	paralysis	J:151335
Mog^tm1(cre)Gkl/Mog^tm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch/0 C57BL/6-Mog^tm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch	increased susceptibility to experimental autoimmune encephalomyelitis	J:151335
Mog^tm1Dpd/Mog^tm1Dpd Rag2^tm1Cgn/Rag2^tm1Cgn Tg(Tcra2D2,Tcrb2D2)1Kuch/0 involves: 129S2/SvPas * C57BL/6	increased susceptibility to experimental autoimmune encephalomyelitis	J:151335
Mog^tm1Dpd/Mog^tm1Dpd Tg(H2-K^b-Tcra,-Tcrb)1640Kurs/0 SJL.Cg-Mog^tm1Dpd Tg(H2-K^b-Tcra,-Tcrb)1640Kurs	decreased susceptibility to experimental autoimmune encephalomyelitis	J:149511
Mog^tm1Dpd/Mog^tm1Dpd Tg(Tcra2D2,Tcrb2D2)1Kuch/0 involves: 129S2/SvPas * C57BL/6	abnormal nervous system morphology	J:151335
	abnormal optic nerve morphology	J:151335
	abnormal spinal cord morphology	J:151335
	CNS inflammation	J:151335
	demyelination	J:151335
	increased susceptibility to experimental autoimmune encephalomyelitis	J:151335
	muscle hypertonia	J:151335
	paralysis	J:151335

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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