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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pappa
pregnancy-associated plasma protein A
MGI:97479
23 phenotypes from 6 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pappam1Btlr/Pappam1Btlr
C57BL/6J-Pappam1Btlr 		decreased body weight J:272859
decreased bone mineral content J:272859
decreased bone mineral density J:272859
decreased bone mineral density of femur J:272859
decreased lean body mass J:272859
Pappam1Btlr/Pappam1Btlr
C57BL/6J-Pappam1Btlr/Btlr 		decreased bone mineral density J:309727
decreased bone mineral density of femur J:309727
short tibia J:309727
small pubis J:309727
PappaM2Btlr/PappaM2Btlr
C57BL/6J-PappaM2Btlr 		decreased body weight J:272860
Pappam3Btlr/Pappam3Btlr
C57BL/6J-Pappam3Btlr 		decreased body weight J:272861
Pappam4Btlr/Pappam4Btlr
C57BL/6J-Pappam4Btlr 		decreased body weight J:274970
Pappatm1Cac/Pappatm1Cac
involves: 129 * C57BL/6 		abnormal enzyme/coenzyme activity J:161983
abnormal enzyme/coenzyme level J:161983
decreased birth body size J:88578
decreased body length J:88578
decreased body weight J:88578, J:161983
decreased circulating estradiol level J:161983
decreased circulating progesterone level J:161983
decreased litter size J:161983
decreased ovary weight J:161983
decreased superovulation rate J:161983
delayed bone ossification J:88578
increased circulating estradiol level J:161983
proportional dwarf J:88578
reduced female fertility J:161983
small ovary J:161983
Pappatm1Lex/Pappatm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:201775
Pappatm1Lex/Pappatm1Lex
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S5/SvEvBrd * C57BL/6 * CBA 		abnormal vascular wound healing J:201775
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory