Pax2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pax2
paired box 2
MGI:97486

43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Eya1^tm1Rilm/Eya1⁺ Pax2^tm1Pgr/Pax2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
	small vestibular saccule	J:119574
Eya1^tm1Rilm/Eya1⁺ Pax2^tm1Pgr/Pax2⁺ Six1^tm1Mair/Six1⁺ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
	small vestibular saccule	J:119574
Pax2^1Neu/Pax2⁺ Wt1^tm1Jae/Wt1⁺ involves: 102 * 129S4/SvJae * C57BL/6	abnormal kidney calyx morphology	J:86661
	abnormal kidney collecting duct morphology	J:86661
	abnormal kidney development	J:86661
	absent kidney	J:86661
	decreased nephron number	J:86661
	decreased renal glomerulus number	J:86661
	increased kidney apoptosis	J:86661
	kidney medulla hypoplasia	J:86661
	lethality throughout fetal growth and development, incomplete penetrance	J:86661
	postnatal lethality, incomplete penetrance	J:86661
	small kidney	J:86661
Pax2^tm1Mbu/Pax2⁺ Pax8^tm1(cre)Mbu/Pax8⁺ involves: 129P2/OlaHsd * C3H/He * C57BL/6	abnormal metanephric mesenchyme morphology	J:80208
	blind vagina	J:80208
	decreased nephron number	J:80208
	decreased renal glomerulus number	J:80208
	reduced male fertility	J:80208
	renal hypoplasia	J:80208
	small metanephros	J:80208
	vagina atresia	J:80208
Pax2^tm1Mbu/Pax2⁺ Pax8^tm1(cre)Mbu/Pax8^tm1(cre)Mbu involves: 129P2/OlaHsd * C3H/He * C57BL/6	absent metanephros	J:80208
	absent ureter	J:80208
	absent vas deferens	J:80208
Pax2^tm1Mbu/Pax2^tm1Mbu Pax8^tm1(cre)Mbu/Pax8^tm1(cre)Mbu C3.Cg-Pax2^tm1Mbu Pax8^tm1(cre)Mbu	abnormal kidney development	J:80208
Pax2^tm1Mbu/Pax2^tm2(Pax5)Mbu C3.129P2-Pax2^tm1Mbu Pax2^tm2(Pax5)Mbu	abnormal cochlea morphology	J:63683
	abnormal kidney development	J:63683
	abnormal otolith organ morphology	J:63683
	abnormal retina morphology	J:63683
	abnormal retina pigmentation	J:63683
	absent kidney	J:63683
	absent ureter	J:63683
	normal reproductive system phenotype	J:63683
	small kidney	J:63683
	normal vision/eye phenotype	J:63683
Pax2^tm1Pgr/Pax2⁺ Ret^tm1Cos/Ret⁺ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ	absent kidney	J:117753
	absent ureter	J:117753
	decreased renal glomerulus number	J:117753
	impaired branching involved in ureteric bud morphogenesis	J:117753
	preweaning lethality, incomplete penetrance	J:117753
	renal hypoplasia	J:117753
	single kidney	J:117753
Pax2^tm2(Pax5)Mbu/Pax2^tm2(Pax5)Mbu C3.129P2-Pax2^tm2(Pax5)Mbu	abnormal kidney development	J:63683
	abnormal retina morphology	J:63683
	normal hearing/vestibular/ear phenotype	J:63683
	increased kidney apoptosis	J:63683
	kidney failure	J:63683
	normal nervous system phenotype	J:63683
	perinatal lethality, complete penetrance	J:63683
	renal hypoplasia	J:63683
	normal renal/urinary system phenotype	J:63683
	normal reproductive system phenotype	J:63683
	small kidney	J:63683
	normal vision/eye phenotype	J:63683

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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