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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pax5
paired box 5
MGI:97489
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ightm1(PAX5)Mbu/Igh+
Pax5tm1Mbu/Pax5tm1Mbu
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA 		abnormal B cell differentiation J:118111
decreased B cell number J:118111
normal immune system phenotype J:118111
Pax2tm1Mbu/Pax2tm2(Pax5)Mbu
C3.129P2-Pax2tm1Mbu Pax2tm2(Pax5)Mbu 		abnormal cochlea morphology J:63683
abnormal kidney development J:63683
abnormal otolith organ morphology J:63683
abnormal retina morphology J:63683
abnormal retina pigmentation J:63683
absent kidney J:63683
absent ureter J:63683
normal reproductive system phenotype J:63683
small kidney J:63683
normal vision/eye phenotype J:63683
Pax2tm2(Pax5)Mbu/Pax2tm2(Pax5)Mbu
C3.129P2-Pax2tm2(Pax5)Mbu 		abnormal kidney development J:63683
abnormal retina morphology J:63683
normal hearing/vestibular/ear phenotype J:63683
increased kidney apoptosis J:63683
kidney failure J:63683
normal nervous system phenotype J:63683
perinatal lethality, complete penetrance J:63683
renal hypoplasia J:63683
normal renal/urinary system phenotype J:63683
normal reproductive system phenotype J:63683
small kidney J:63683
normal vision/eye phenotype J:63683
Pax5tm3Mbu/Pax5+
Tcf3tm1(PBX1)Mlc/Tcf3+
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * C57BL/6 		abnormal pro-B cell morphology J:226241
arrested B cell differentiation J:226241
decreased immature B cell number J:226241
increased B cell acute lymphoblastic leukemia incidence J:226241
Pax5tm4(CD2*)Mbu/Pax5tm4(CD2*)Mbu
B6.129P2-Pax5tm4(CD2*)Mbu 		normal immune system phenotype J:144100
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory