Pax6 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pax6
paired box 6
MGI:97490

46 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Emx2^tm1Sia/Emx2^tm1Sia Pax6^Sey/Pax6^Sey involves: C57BL/6 * CBA	abnormal Ammon gyrus morphology	J:98539
	abnormal brain commissure morphology	J:98539
	abnormal brain morphology	J:98539
	abnormal cerebral cortex morphology	J:98539
	abnormal embryonic/fetal subventricular zone morphology	J:98539
	abnormal pretectal region morphology	J:98539
	abnormal tectum morphology	J:98539
	abnormal telencephalon morphology	J:98539
	abnormal thalamus morphology	J:98539
	absent choroid plexus	J:98539
	absent diencephalon	J:98539
	absent hippocampus	J:98539
Gli2^tm1Alj/Gli2^tm1Alj Pax6^Sey/Pax6^Sey involves: 129S1/Sv * 129X1/SvJ	abnormal neuron differentiation	J:112802
Mitf^mi-vga9/Mitf⁺ Pax6^Sey-Neu/Pax6⁺ involves: C57BL/6 * CBA	abnormal retina pigment epithelium morphology	J:188155
Mitf^mi-vga9/Mitf^mi-vga9 Pax6^Sey-Neu/Pax6⁺ involves: C57BL/6 * CBA	abnormal retina pigment epithelium morphology	J:188155
Mitf^mi-vga9/Mitf^mi-vga9 Pax6^Sey-Neu/Pax6^Sey-Neu involves: C57BL/6 * CBA	abnormal retina pigment epithelium morphology	J:188155
Mitf^tm3.1Arnh/Mitf^tm3.1Arnh Pax6^Sey-Neu/Pax6⁺ involves: 129S6/SvEvTac * C57BL/6N	abnormal retina pigment epithelium morphology	J:188155
Pax6^Sey-H/Pax6⁺ involves: 101/H * C3H/HeH	belly spot	J:8534
	coloboma	J:8534
	decreased body size	J:8534
	lowered ear position	J:8534
	microphthalmia	J:8534
	reduced female fertility	J:8534
	small ears	J:8534
Pax6^Sey-H/Pax6^Sey-H involves: 101/H * C3H/HeH	embryonic lethality, complete penetrance	J:8534
Pax6^Sey-Neu/Pax6⁺ Sox2^tm1.1Vep/Sox2⁺ involves: 102 * C3H * C3H/HeN	abnormal lens morphology	J:119175
Pax6^Sey/Pax6^Sey-H involves: 101/H * C3H/HeH * C57BL/10	abnormal face development	J:8534
	abnormal maxillary shelf morphology	J:8534
	absent snout	J:8534
	anophthalmia	J:8534
	decreased embryo size	J:8534
Pax6^Sey/Pax6^Sey-Neu Tg(Hbb-b1)83Clo/0 involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL	abnormal craniofacial bone morphology	J:43913
	abnormal nasal capsule morphology	J:43913
	supernumerary incisors	J:43913
Pax6^Sey/Pax6^Sey Tg(Hbb-b1)83Clo/0 involves: C57BL * CBA/Ca * CD-1 * SJL	abnormal craniofacial bone morphology	J:43913
	abnormal nasal capsule morphology	J:43913
	supernumerary incisors	J:43913
Pax6^Sey/Pax6^Sey Tg(PAX6)77Ndha/? involves: C57BL/6 * CBA	normal nervous system phenotype	J:34194
	normal taste/olfaction phenotype	J:34194
	normal vision/eye phenotype	J:34194
Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6⁺ involves: 129S6/SvEvTac	normal vision/eye phenotype	J:198381
Pax6^{tm2(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2(Pax6_i5a,Pax2)Xzh} involves: 129S6/SvEvTac	abnormal eye development	J:198381
	abnormal neuronal precursor proliferation	J:198381
	abnormal retina development	J:198381
	abnormal telencephalon development	J:198381
	thin cortical plate	J:198381
Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6⁺ involves: 129S6/SvEvTac * C57BL/6 * FVB/N	corneal-lenticular stalk	J:198381
Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh}/Pax6^{tm2.1(Pax6_i5a,Pax2)Xzh} involves: 129S6/SvEvTac * C57BL/6 * FVB/N	abnormal cortical plate morphology	J:198381
	abnormal eye development	J:198381
	abnormal neuronal precursor proliferation	J:198381
	abnormal retina development	J:198381
	abnormal telencephalon development	J:198381
Pax6^tm2Pgr/Pax6^tm2Pgr Smarcc2^tm1.1Stoy/Smarcc2⁺ Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S1/Sv * 129S2/SvPas * C57BL/6	abnormal neuron number	J:197141
	normal nervous system phenotype	J:197141
Pax6^tm2Pgr/Pax6^tm2Pgr Smarcc2^tm1.1Stoy/Smarcc2^tm1.1Stoy Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S1/Sv * 129S2/SvPas * C57BL/6	abnormal neocortex morphology	J:197141
	abnormal neuron number	J:197141
	abnormal neuronal precursor cell number	J:197141
Pax6^tm2Pgr/Pax6^tm2Pgr Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Cryaa-cre)10Mlr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	abnormal lens epithelium morphology	J:152850
	increased lens epithelium apoptosis	J:152850
	microphthalmia	J:152850

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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