Pax7 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pax7
paired box 7
MGI:97491

52 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
2310065F04Rik^tm1.1Boet/2310065F04Rik^tm1.1Boet Ino80^tm1.1Jland/Ino80^tm1.1Jland Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ	normal growth/size/body region phenotype	J:306156
	normal muscle phenotype	J:306156
2310065F04Rik^tm1.1Boet/2310065F04Rik^tm1.1Boet Ino80^tm1.1Jland/Ino80^tm1.1Jland Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl	normal muscle phenotype	J:306156
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Pax7^tm1(cre)Mrc/? B6.Cg-Pax7^tm1(cre)Mrc Abcc6^{tm1c(EUCOMM)Wtsi}	normal integument phenotype	J:252837
Ar^tm2Ska/Ar^tm2Ska Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrl	normal muscle phenotype	J:316008
Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs Pax7^tm1Pgr/Pax7⁺ Tg(CKMM-tTA)A3Rhvh/0 Tg(tetO-Hgf,-EGFP)24Tcre/0 involves: 129S2/SvPas * 129X1/SvJ * FVB	increased rhabdomyosarcoma incidence	J:237183
	increased sarcoma incidence	J:237183
Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs Pax7^tm1Pgr/Pax7^tm1Pgr Tg(CKMM-tTA)A3Rhvh/0 Tg(tetO-Hgf,-EGFP)24Tcre/0 involves: 129S2/SvPas * 129X1/SvJ * FVB	increased rhabdomyosarcoma incidence	J:237183
	increased sarcoma incidence	J:237183
Dbx1^tm1(DTA)Apie/Dbx1⁺ Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	normal nervous system phenotype	J:165285
Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor^tm1(EYFP)Cos Pax7^{tm1(cre/ERT2)Gaka}/Pax7^{tm1(cre/ERT2)Gaka} Paxbp1^tm1.1Nju/Paxbp1^tm1.1Nju involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCr	abnormal mitochondrial ATP synthesis coupled electron transport	J:304562
	abnormal mitochondrial morphology	J:304562
	abnormal oxidative phosphorylation	J:304562
	abnormal respiratory electron transport chain	J:304562
	decreased mitochondrial fission	J:304562
	impaired skeletal muscle regeneration	J:304562
Gt(ROSA)26Sor^{tm1.1(DUX4)Plj}/Gt(ROSA)26Sor⁺ Pax7^{tm1(cre/ERT2)Gaka}/? involves: 129S6/SvEvTac C57BL/6 * C57BL/6NCrl	no abnormal phenotype detected	J:256652
Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Pax7^tm1.1Fan/Pax7^{tm2.1(cre/ERT2)Fan} involves: 129 * C57BL/6 * SJL	abnormal muscle regeneration	J:150962
	abnormal myogenesis	J:150962
	normal muscle phenotype	J:150962
Gt(ROSA)26Sor^tm2(SS18)Mrc/Gt(ROSA)26Sor^tm2(SS18)Mrc Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	lethality throughout fetal growth and development, complete penetrance	J:120967
Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc}/Gt(ROSA)26Sor^{tm3(SS18/EGFP)Mrc} Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal muscle development	J:120967
	lethality throughout fetal growth and development, complete penetrance	J:120967
Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor⁺ Kdm6a^tm1.1Kaig/Y Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	impaired skeletal muscle regeneration	J:232700
Gt(ROSA)26Sor^{tm4(EWSR1/ATF1)Mrc}/Gt(ROSA)26Sor⁺ Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal craniofacial morphology	J:194308
	lethality throughout fetal growth and development, complete penetrance	J:194308
Gt(ROSA)26Sor^{tm4(EWSR1/ATF1)Mrc}/Gt(ROSA)26Sor⁺ Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ involves: 129S6/SvEvTac * C57BL/6	myopathy	J:194308
	normal neoplasm	J:194308
Ino80^tm1.1Jland/Ino80^tm1.1Jland Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ	normal muscle phenotype	J:306156
Kdm6a^tm1.1Kaig/Kdm6a^tm1.1Kaig Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal muscle precursor cell morphology	J:232700
	impaired skeletal muscle regeneration	J:232700
Kdm6a^tm1.1Kaig/Y Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal muscle precursor cell morphology	J:232700
	impaired skeletal muscle regeneration	J:232700
Kras^tm4Tyj/Kras⁺ Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ Trp53^tm1Brn/Trp53^tm1Brn involves: 129/Sv * 129P2/OlaHsd * 129X1/SvJ * C57BL/6	increased sarcoma incidence	J:205518
	increased tumor incidence	J:205518
Mamstr^tm1.1Eno/Mamstr^tm1.1Eno Pax7^{tm2.1(cre/ERT2)Fan}/Pax7⁺ involves: 129 * C57BL/6	impaired skeletal muscle regeneration	J:179880
Myf5^tm1(cre)Mrc/Myf5⁺ Myod1^tm1Jae/Myod1^tm1Jae Pax7^tm1.1Thbr/Pax7^tm1.1Thbr involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	decreased satellite cell number	J:202693
Myf5^tm1Tajb/Myf5^tm1Tajb Pax7^tm1.1Tajb/Pax7^tm1.1Tajb involves: 129S2/SvPas	abnormal extraocular muscle morphology	J:150130
	normal muscle phenotype	J:150130
Myh3^tm1.2Sajm/Myh3^tm1.1Sajm Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J	abnormal muscle precursor cell morphology	J:287755
	normal cellular phenotype	J:287755
Pax3^tm1.1Sjc/Pax3^tm1.1Sjc Pax7^tm1.2Fan/Pax7^tm1.2Fan Tg(CAG-cre/Esr1)5Amc/0 involves: 129 C57BL/6 * CBA * SJL	normal muscle phenotype	J:150962
Pax3^tm1Buck/Pax3^tm1Buck Pax7^tm2Pgr/Pax7^tm2Pgr either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas)	abnormal myotome development	J:99365
	prenatal lethality, complete penetrance	J:99365
Pax3^tm1Mrc/Pax3⁺ Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal nose morphology	J:93443
	abnormal premaxilla morphology	J:93443
	decreased body weight	J:93443
	decreased satellite cell number	J:93443
	decreased skeletal muscle fiber diameter	J:93443
	decreased skeletal muscle mass	J:93443
	increased skeletal muscle fiber density	J:93443
	lacrimal bone hypoplasia	J:93443
	maxilla hypoplasia	J:93443
	muscle hypoplasia	J:93443
	normal neoplasm	J:93443
	postnatal growth retardation	J:93443
	premature death	J:93443
	turbinate hypoplasia	J:93443
Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc Paxbp1^tm1.1Nju/Paxbp1^tm1.1Nju involves: 129S1/Sv * 129X1/SvJ	embryonic lethality, complete penetrance	J:304562
Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ Gt(ROSA)26Sor^tm1(DTA)Mrc/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	decreased satellite cell number	J:174914
	impaired skeletal muscle regeneration	J:174914
	skeletal muscle fibrosis	J:174914
Pax7^{tm1(cre/ERT2)Gaka}/0 Snhg15^tm1.1Nju/Snhg15^tm1.1Nju involves: C57BL/6J * SJL/J	delayed skeletal muscle regeneration	J:291983
Pax7^{tm1.1(HBEGF,-EYFP)Mal}/Pax7⁺ involves: C57BL/6	decreased skeletal muscle mass	J:180899
	impaired skeletal muscle regeneration	J:180899
	normal muscle phenotype	J:180899
	myositis	J:180899
Pax7^{tm1.1(HBEGF,-EYFP)Mal}/Pax7⁺ Tg(Pax7-EGFP)15Tajb/0 involves: C57BL/6 * SJL/J	abnormal muscle regeneration	J:180899
	decreased satellite cell number	J:180899
Pax7^{tm1.1(HBEGF,-EYFP)Mal}/Pax7^{tm1.1(HBEGF,-EYFP)Mal} involves: C57BL/6	decreased birth body size	J:180899
	premature death	J:180899
Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl} Tg(Myl1-FST)F66Sjl/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal skeletal muscle fiber size	J:188599
	increased skeletal muscle weight	J:188599
Prmt7^tm1.1Rchd/Prmt7^tm1.1Rchd Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6NCrl	abnormal muscle physiology	J:271361
	abnormal response to injury	J:271361
	early cellular replicative senescence	J:271361
	impaired skeletal muscle regeneration	J:271361
Ptch1^tm1Cklr/Ptch1⁺ Trp53^tm1Brn/? Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	increased medulloblastoma incidence	J:159972
Ptch1^tm1Cklr/Ptch1⁺ Pax7^tm1(cre)Mrc/Pax7⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	ataxia	J:159972
	increased medulloblastoma incidence	J:159972
Six1^tm2.1Mair/Six1^tm2.1Mair Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6Cr * C57BL/6NTac	abnormal muscle physiology	J:190460
	abnormal muscle regeneration	J:190460
	normal muscle phenotype	J:190460
	skeletal muscle fibrosis	J:190460
Zfp422^em1Mode/Zfp422^em1Mode Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	abnormal myoblast differentiation	J:297035
	impaired skeletal muscle regeneration	J:297035

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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