Pck1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
MGI:97501

41 phenotypes from 5 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pck1^tm1.1Lre/Pck1^tm1.1Lre involves: 129P2/OlaHsd * BALB/c * C57BL/6	abnormal brown fat cell morphology	J:73977
	abnormal white adipose tissue physiology	J:73977
	abnormal white fat cell morphology	J:73977
	decreased abdominal adipose tissue amount	J:73977
	decreased brown fat cell number	J:73977
	decreased brown fat cell size	J:73977
	decreased circulating ketone body level	J:73977
	decreased circulating triglyceride level	J:73977
	decreased epididymal fat pad weight	J:73977
	decreased liver triglyceride level	J:73977
	decreased white adipose tissue amount	J:73977
	decreased white fat cell lipid droplet size	J:73977
	decreased white fat cell size	J:73977
	normal homeostasis/metabolism phenotype	J:73977
	hyperglycemia	J:73977
	lipodystrophy	J:73977
Pck1^tm1.1Mgn/Pck1^tm1.1Mgn involves: 129S6/SvEvTac	no abnormal phenotype detected	J:63929
Pck1^tm1.1Mgn/Pck1^tm1.1Mgn Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S6/SvEvTac	decreased liver glycogen level	J:63929
	enlarged liver	J:63929
	increased circulating free fatty acids level	J:63929
	increased circulating triglyceride level	J:63929
	increased liver triglyceride level	J:63929
	increased liver weight	J:63929
	pale liver	J:63929
Pck1^tm1.2Mgn/Pck1^tm1.2Mgn involves: 129S6/SvEvTac	absent gastric milk in neonates	J:63929
	decreased body size	J:63929
	decreased liver glycogen level	J:63929
	hypoglycemia	J:63929
	lethargy	J:63929
	pale liver	J:63929
	pallor	J:63929
	postnatal lethality, complete penetrance	J:63929
Pck1^tm1Mgn/Pck1^tm1.2Mgn involves: 129S6/SvEvTac	enlarged liver	J:63929
Pck1^tm1Mgn/Pck1^tm1.2Mgn involves: 129S6/SvEvTac	pale liver	J:63929
Pck1^tm1Mgn/Pck1^tm1Mgn involves: 129S6/SvEvTac	enlarged liver	J:63929
Pck1^tm1Rwh/Pck1^tm1Rwh involves: 129P2/OlaHsd * C57BL/6	abnormal circulating amino acid level	J:145210
	abnormal circulating lipid level	J:145210
	abnormal liver morphology	J:145210
	abnormal postnatal growth	J:145210
	decreased circulating glucose level	J:145210
	decreased liver glycogen level	J:145210
	decreased percent body fat/body weight	J:145210
	hepatic steatosis	J:145210
	increased blood urea nitrogen level	J:145210
	increased circulating ammonia level	J:145210
	increased circulating ketone body level	J:145210
	increased circulating lactate level	J:145210
	increased circulating triglyceride level	J:145210
	postnatal lethality, complete penetrance	J:145210

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