Pcna Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pcna
proliferating cell nuclear antigen
MGI:97503

16 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pcna^tm1.1Mdsc/Pcna^tm1.1Mdsc Not Specified	embryonic lethality before implantation, complete penetrance	J:141098
Pcna^tm1.1Mdsc/Pcna^tm1.1Mdsc Tg(Pcna*K164R)1Mdsc/0 involves: FVB/N	abnormal class switch recombination	J:141098
	abnormal meiosis	J:141098
	abnormal somatic hypermutation frequency	J:141098
	arrest of spermatogenesis	J:141098
	infertility	J:141098
	normal mortality/aging	J:141098
	small testis	J:141098
Pcna^tm1.1Scwh/Pcna^tm1.1Scwh involves: FVB	abnormal adipose tissue development	J:193874
	decreased body weight	J:193874
	decreased percent body fat/body weight	J:193874
	decreased susceptibility to weight gain	J:193874
	decreased white fat cell number	J:193874
	increased lean body mass	J:193874
Pcna^tm1Jcbs/Pcna^tm1Jcbs involves: 129P2/OlaHsd	abnormal somatic hypermutation frequency	J:155454, J:177630
Pcna^tm1Jcbs/Pcna^tm1Jcbs involves: 129P2/OlaHsd * C57BL/6	abnormal somatic hypermutation frequency	J:125916
	absent germ cells	J:125916
	embryonic lethality during organogenesis, incomplete penetrance	J:125916
	infertility	J:125916

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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