Pdgfa Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdgfa
platelet derived growth factor, alpha
MGI:97527

29 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pdgfa^tm1Cbet/Pdgfa⁺ Pdgfc^tm1Nagy/Pdgfc^tm1Nagy involves: 129S1/Sv * 129X1/SvJ * C57BL/6	spina bifida	J:205009
Pdgfa^tm1Cbet/Pdgfa^tm1Cbet Pdgfc^tm1Nagy/Pdgfc^tm1Nagy involves: 129S1/Sv * 129X1/SvJ	abnormal axial skeleton morphology	J:93954
	abnormal craniofacial bone morphology	J:93954
	abnormal kidney cortex morphology	J:93954
	abnormal myotome development	J:93954
	abnormal scapula morphology	J:93954
	abnormal somite development	J:93954
	blistering	J:93954
	common atrium	J:93954
	decreased embryo size	J:93954
	embryonic lethality during organogenesis, complete penetrance	J:93954
	hydrops fetalis	J:93954
	midline facial cleft	J:93954
	pericardial effusion	J:93954
	rib bifurcation	J:93954
	rib fusion	J:93954
	short sternum	J:93954
	spina bifida	J:93954
	wavy neural tube	J:93954
Pdgfa^tm1Cbet/Pdgfa^tm2Cbet Pdgfra^{tm11(EGFP)Sor}/Pdgfra⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	abnormal lung morphology	J:205009
	abnormal pulmonary alveolus morphology	J:205009
	normal digestive/alimentary phenotype	J:205009
	emphysema	J:205009
	normal renal/urinary system phenotype	J:205009
	normal skeleton phenotype	J:205009
Pdgfa^tm2Cbet/Pdgfa^tm2Cbet Pdgfc^tm1Nagy/Pdgfc^tm1Nagy B6.129-Pdgfc^tm1Nagy Pdgfa^tm2Cbet	spina bifida	J:205009
	spina bifida occulta	J:205009
Pdgfa^tm2Cbet/Pdgfa^tm2Cbet Pdgfc^tm1Nagy/Pdgfc^tm1Nagy involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal small intestine morphology	J:205009
	decreased body size	J:205009
	decreased small intestinal villus number	J:205009
	kyphosis	J:205009
	spina bifida	J:205009
	spina bifida occulta	J:205009

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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