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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pdgfb
platelet derived growth factor, B polypeptide
MGI:97528
7 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sor+
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		abnormal blood vessel morphology J:166532
Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sor+
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL 		abnormal astrocyte morphology J:166532
abnormal capillary morphology J:166532
abnormal pericyte morphology J:166532
decreased capillary density J:166532
impaired blood-brain barrier function J:166532
Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sortm1(PDGFB)Cbet
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		normal cardiovascular system phenotype J:166532
Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sortm1(PDGFB)Cbet
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL 		abnormal astrocyte morphology J:166532
abnormal capillary morphology J:166532
abnormal pericyte morphology J:166532
decreased capillary density J:166532
impaired blood-brain barrier function J:166532
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory