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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pepd
peptidase D
MGI:97542
67 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pepddal/Pepddal
CBA/J-Pepddal/GrsrJ 		abnormal urine homeostasis J:87005
darkened coat color J:143333
decreased body size J:87005, J:143333
decreased oocyte number J:87005
irregular coat pigmentation J:87005
Pepddal/Pepddal
involves: C3H/HeJ * C3HeB/FeJ * CBA/J 		abnormal testis morphology J:143333
brain vacuoles J:143333
Pepddal/Pepddal
involves: C3H/HeJ * CBA/J 		abnormal aorta collagen fibril morphology J:215150
abnormal cardiac muscle tissue morphology J:215150
abnormal heart morphology J:215150
abnormal heart septum morphology J:215150
abnormal myocardial fiber morphology J:215150
abnormal seminiferous tubule morphology J:143333
abnormal testis interstitial tissue morphology J:143333
abnormal testis morphology J:143333
atrioventricular septal defect J:215150
brain vacuoles J:143333
darkened coat color J:143333, J:215150
decreased circulating testosterone level J:143333
decreased collagen level J:215150
embryonic growth retardation J:215150
increased atrioventricular cushion size J:215150
increased fetal cardiomyocyte size J:215150
myocardium hypertrophy J:215150
postnatal lethality, incomplete penetrance J:215150
prenatal lethality, incomplete penetrance J:215150
small testis J:143333
thick interventricular septum J:215150
thick ventricular wall J:215150
ventricular septal defect J:215150
Pepddal/Pepddal
involves: CAST/EiJ * CBA/J 		abnormal agouti pigmentation J:215150
darkened coat color J:215150
decreased body size J:143333
preweaning lethality J:215150
Pepdtm1a(KOMP)Wtsi/Pepdtm1a(KOMP)Wtsi
C57BL/6N-Pepdtm1a(KOMP)Wtsi/Ucd 		abnormal bone structure J:211773
abnormal cornea morphology J:211773
abnormal joint morphology J:211773
abnormal retina morphology J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased immature B cell number J:211773
decreased Ly6C-positive NK T cell number J:211773
decreased mean corpuscular hemoglobin J:211773
decreased transitional stage T1 B cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased circulating insulin level J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased leukocyte cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker NK cell number J:211773
Pepdtm1b(KOMP)Wtsi/Pepdtm1b(KOMP)Wtsi
C57BL/6N-Pepdtm1b(KOMP)Wtsi/Ieg 		abnormal behavior J:211773
abnormal optic disk morphology J:211773
abnormal retina morphology J:211773
decreased B cell number J:211773
decreased B-2 B cell number J:211773
decreased bone mineral content J:211773
decreased CD5-positive Ly6C-positive T cell number J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating iron level J:211773
decreased follicular B cell number J:211773
decreased grip strength J:211773
decreased heart rate J:211773
decreased locomotor activity J:211773
decreased vertical activity J:211773
enlarged lymph nodes J:211773
hyperactivity J:211773
increased circulating aspartate transaminase level J:211773
increased circulating unsaturated transferrin level J:211773
increased thigmotaxis J:211773
prolonged RR interval J:211773
short tibia J:211773
small stomach J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory