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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pgr
progesterone receptor
MGI:97567
56 phenotypes from 10 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pgrtm1.1(cre)Shah/?
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:196278
Pgrtm1.1Mlia/Pgrtm1.1Mlia
involves: 129 * C57BL/6J 		no abnormal phenotype detected J:114465
Pgrtm1.1Mlia/Pgrtm1.1Mlia
Tg(Cdh5-cre)7Mlia/0
involves: 129X1/SvJ * FVB/N 		abnormal uterus physiology J:205553
abnormal vascular permeability J:205553
impaired embryo implantation J:205553
Pgrtm1.2Mlia/Pgrtm1.2Mlia
involves: 129 * C57BL/6J 		failure of superovulation J:114465
female infertility J:114465
Pgrtm1.2Mlia/Pgrtm1.2Mlia
involves: 129X1/SvJ 		abnormal uterus development J:205553
abnormal uterus physiology J:205553
Pgrtm1Bwo/Pgrtm1Bwo
either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6) 		abnormal branching of the mammary ductal tree J:28980
abnormal decidualization J:28980
abnormal mammary gland development J:28980
abnormal mating receptivity J:28980
abnormal uterus morphology J:28980
absent corpus luteum J:28980
dilated uterus J:28980
enlarged endometrial glands J:28980
failure of superovulation J:28980
female infertility J:28980
impaired luteinization J:28980
increased mature ovarian follicle number J:28980
uterus hyperplasia J:28980
uterus inflammation J:28980
Pgrtm1Bwo/Pgrtm1Bwo
involves: 129S7/SvEvBrd 		abnormal bone ossification J:145383
abnormal humerus morphology J:145383
abnormal mammary gland alveolus morphology J:85196
abnormal mammary gland epithelium morphology J:87522
abnormal mammary gland physiology J:158406
abnormal osteoclast morphology J:145383
abnormal response/metabolism to endogenous compounds J:118403
abnormal tibia morphology J:145383
abnormal trabecular bone morphology J:145383
abnormal uterus physiology J:158406
abnormal vascular wound healing J:118403
decreased incidence of induced tumors J:87522
decreased mammary gland epithelial cell proliferation J:85196
failure of superovulation J:158406
increased bone mass J:145383
increased circulating prolactin level J:85196
increased compact bone thickness J:145383
increased trabecular bone thickness J:145383
vascular smooth muscle hyperplasia J:118403
Pgrtm1Bwo/Pgrtm1Bwo
involves: 129S7/SvEvBrd * C57BL/6 		abnormal follicle stimulating hormone level J:56917
decreased circulating luteinizing hormone level J:56917
Pgrtm1Bwo/Pgrtm1Bwo
involves: 129S7/SvEvBrd * C57BL/6J 		decreased circulating glucose level J:125584
improved glucose tolerance J:125584
increased circulating insulin level J:125584
increased insulin secretion J:125584
increased pancreatic beta cell number J:125584
increased pancreatic beta cell proliferation J:125584
pancreatic islet hyperplasia J:125584
Pgrtm1Lyd/Pgr+
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:79968
Pgrtm1Lyd/Pgrtm1Lyd
involves: 129S7/SvEvBrd 		abnormal cytokine secretion J:130208
Pgrtm1Lyd/Pgrtm1Lyd
involves: 129S7/SvEvBrd * C57BL/6 		abnormal female reproductive system morphology J:79968
abnormal mammary gland development J:79968
abnormal ovulation J:79968
abnormal reproductive system physiology J:79968
abnormal sexual interaction J:79968
absent corpus luteum J:79968
female infertility J:79968
uterus hyperplasia J:79968
Pgrtm1Omc/Pgrtm1Omc
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal decidualization J:77661
abnormal uterine environment J:77661
decreased superovulation rate J:77661
normal endocrine/exocrine gland phenotype J:77661
female infertility J:77661
uterus hyperplasia J:77661
Pgrtm2Omc/Pgrtm2Omc
involves: 129S7/SvEvBrd * C57BL/6 		abnormal branching of the mammary ductal tree J:85196
abnormal lactation J:85196
abnormal mammary gland alveolus morphology J:85196
abnormal mammary gland epithelium morphology J:85196
abnormal mammary gland growth during pregnancy J:85196
normal reproductive system phenotype J:85196
Pgrtm2Shah/Pgrtm2Shah
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:196278
Pgrtm3(rtTA2S*M2)Lyd/Pgrtm3(rtTA2S*M2)Lyd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal female reproductive system morphology J:128735
abnormal sexual interaction J:128735
female infertility J:128735
Pgrtm4.2Lyd/Pgrtm4.2Lyd
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * FVB/N 		abnormal mammary gland physiology J:158406
abnormal uterus physiology J:158406
failure of superovulation J:158406
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11/12/2024
MGI 6.24 		The Jackson Laboratory