About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pgr
progesterone receptor
MGI:97567
83 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Apctm1Rsmi/Apctm1Rsmi
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal internal female genitalia morphology J:210095
abnormal oviduct morphology J:210095
endometrium hyperplasia J:210095
increased granulosa cell tumor incidence J:210095
increased ovary tumor incidence J:210095
increased reproductive system tumor incidence J:210095
ovary cyst J:210095
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
abnormal decidualization J:287978
decreased litter size J:287978
impaired embryo implantation J:287978
reduced female fertility J:287978
Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal uterus morphology J:150007
endometrium hyperplasia J:150007
female infertility J:150007
increased endometrial carcinoma incidence J:150007
increased endometrial gland number J:150007
increased uterus weight J:150007
Errfi1tm1Jwj/Errfi1tm1Jwj
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
abnormal endometrium morphology J:162027
endometrium hyperplasia J:162027
increased endometrial carcinoma incidence J:162027
increased metastatic potential J:162027
increased uterus weight J:162027
premature death J:162027
Ezh2tm2Sho/Ezh2tm2Sho
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal endometrial gland morphology J:290765
abnormal endometrium morphology J:290765
abnormal parturition J:290765
abnormal uterine epithelium development J:290765
decreased litter size J:290765
decreased uterine NK cell number J:290765
dystocia J:290765
endometrium hyperplasia J:290765
enlarged uterine horn J:290765
increased endometrial gland number J:290765
reduced female fertility J:290765
Foxa2tm1Khk/Foxa2tm1Khk
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal decidualization J:165229
abnormal embryo invasion J:165229
abnormal endometrial gland development J:165229
abnormal uterus physiology J:165229
decreased endometrial gland number J:165229
decreased litter size J:165229
impaired embryo implantation J:165229
reduced female fertility J:165229
Gata2tm1Sac/Gata2tm1Sac
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal decidualization J:240902
abnormal endometrium morphology J:240902
abnormal uterus physiology J:240902
failure of embryo implantation J:240902
female infertility J:240902
Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:218222
Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
abnormal uterus physiology J:218222
endometrium hyperplasia J:218222
increased papilloma incidence J:218222
increased uterus weight J:218222
premature death J:218222
Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts/Gt(ROSA)26Sor+
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
normal reproductive system phenotype J:162256
Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
Gt(ROSA)26Sortm2(CAG-Nr5a1)Fjd/Gt(ROSA)26Sor+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal decidualization J:269597
abnormal endometrial gland development J:269597
abnormal endometrial gland morphology J:269597
abnormal endometrium morphology J:269597
abnormal uterus morphology J:269597
enlarged endometrial glands J:269597
enlarged uterine horn J:269597
female infertility J:269597
uterus cyst J:269597
uterus inflammation J:269597
Hdac3tm1.1Eno/Hdac3tm1.1Eno
Pgrtm2(cre)Lyd/Pgr+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal decidualization J:269518
abnormal embryo attachment J:269518
abnormal endometrium morphology J:269518
abnormal uterine receptivity J:269518
abnormal uterus physiology J:269518
endometrium fibrosis J:269518
failure of embryo implantation J:269518
female infertility J:269518
normal homeostasis/metabolism phenotype J:269518
increased collagen level J:269518
normal reproductive system phenotype J:269518
Klf5tm1Jaw/Klf5tm1Jaw
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal decidualization J:179912
abnormal embryo attachment J:179912
abnormal uterine receptivity J:179912
decreased litter size J:179912
failure of embryo implantation J:179912
female infertility J:179912
normal homeostasis/metabolism phenotype J:179912
impaired embryo implantation J:179912
reduced female fertility J:179912
Leprtm1.1Chua/Leprtm1.1Chua
Pgrtm2(cre)Lyd/Pgr+
involves: 129 * C57BL/6J * FVB/NJ
abnormal embryo implantation J:324160
abnormal parturition J:324160
decreased litter size J:324160
delayed parturition J:324160
dystocia J:324160
normal embryo phenotype J:324160
normal homeostasis/metabolism phenotype J:324160
pup cannibalization J:324160
reduced female fertility J:324160
normal reproductive system phenotype J:324160
Men1tm1.2Zqw/Men1tm1.2Zqw
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal decidualization J:322043
abnormal DNA methylation J:322043
abnormal embryo development J:322043
abnormal placenta development J:322043
abnormal trophoblast giant cell morphology J:322043
decreased litter size J:322043
decreased uterine NK cell number J:322043
embryonic growth retardation J:322043
impaired embryo implantation J:322043
increased endometrial gland number J:322043
increased miscarriage rate J:322043
reduced female fertility J:322043
Ncoa1tm1Bwo/Ncoa1tm1Bwo
Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc
Pgrtm2(cre)Lyd/Pgr+
involves: 129/Sv * 129S1/Sv * 129S2/SvPas * 129X1/SvJ
abnormal decidualization J:117006
Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
abnormal branching of the mammary ductal tree J:117006
abnormal decidualization J:117006
failure of embryo implantation J:117006
female infertility J:117006
normal reproductive system phenotype J:117006
Ncoa6tm3Jxu/Ncoa6tm3Jxu
Pgrtm2(cre)Lyd/Pgr+
involves: 129/Sv * C57BL/6 * SJL
abnormal decidualization J:189065
abnormal luminal closure J:189065
abnormal uterine receptivity J:189065
female infertility J:189065
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
female infertility J:162256
Pgrtm2(cre)Lyd/Pgr+
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
normal reproductive system phenotype J:139053
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
abnormal uterus physiology J:162027
decreased uterus weight J:218222
endometrium hyperplasia J:162027
increased endometrial carcinoma incidence J:162027, J:218222
increased papilloma incidence J:218222
increased uterus weight J:162027, J:218222
premature death J:218222
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
endometrium hyperplasia J:139053
increased endometrial carcinoma incidence J:139053
premature death J:139053
Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu
Trp53tm1Brn/Trp53tm1Brn
involves: 129 * C57BL/6
endometrium hyperplasia J:139053
enlarged uterus J:139053
increased endometrial carcinoma incidence J:139053
premature death J:139053
Pgrtm2(cre)Lyd/Pgr+
Rbpjtm1Hon/Rbpjtm1Hon
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
abnormal decidualization J:326956
Pgrtm2(cre)Lyd/Pgr+
Criptotm2.2Mms/Criptotm2.2Mms
involves: 129/Sv * C57BL/6N * CD-1
abnormal decidualization J:324146
abnormal embryo attachment J:324146
abnormal endometrial gland morphology J:324146
abnormal luminal closure J:324146
abnormal pregnancy J:324146
abnormal uterine environment J:324146
abnormal uterine-embryonic axis J:324146
decreased litter size J:324146
delayed embryo implantation J:324146
endometrium inflammation J:324146
failure of embryo implantation J:324146
female infertility J:324146
reduced female fertility J:324146
Pgrtm2(cre)Lyd/Pgr+
Ror1tm1.1Meg/Ror1tm1.1Meg
Ror2tm1.1Meg/Ror2tm1.1Meg
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
abnormal embryo attachment J:233595
abnormal maternal decidual layer morphology J:233595
decreased litter size J:233595
reduced female fertility J:233595
Pgrtm2(cre)Lyd/Pgr+
Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
involves: 129S1/Sv * 129X1/SvJ
abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp
Pgrmc2tm1.1Jjp/Pgrmc2+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
enlarged endometrial glands J:247103
Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp
Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal endometrial gland morphology J:247103
abnormal endometrium morphology J:247103
decreased litter size J:247103
early reproductive senescence J:247103
enlarged endometrial glands J:247103
increased endometrial gland number J:247103
reduced female fertility J:247103
uterus cyst J:247103
Pgrmc2tm1.1Jjp/Pgrmc2+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
enlarged endometrial glands J:247103
Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal endometrial gland morphology J:247103
abnormal endometrium morphology J:247103
decreased circulating progesterone level J:247103
decreased litter size J:247103
decreased uterine NK cell number J:247103
early reproductive senescence J:247103
enlarged endometrial glands J:247103
increased endometrial gland number J:247103
reduced female fertility J:247103
uterus cyst J:247103
Phb1tm1.1Bwo/Phb1tm1.1Bwo
Pgrtm2(cre)Lyd/?
involves: 129S7/SvEvBrd * C57BL/6
abnormal endometrium morphology J:173884
abnormal uterus morphology J:173884
abnormal uterus size J:173884
decreased uterus weight J:173884
normal endocrine/exocrine gland phenotype J:173884
endometrium hypoplasia J:173884
female infertility J:173884
normal homeostasis/metabolism phenotype J:173884
thin uterine horn J:173884
Phb2tm2.1Katz/Phb2+
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal mammary gland duct morphology J:178347
Phb2tm2.1Katz/Phb2tm2.1Katz
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal mammary gland duct morphology J:178347
abnormal mammary gland morphology J:178347
normal reproductive system phenotype J:178347
Tg(CMV-GAL4)1Shy/0
Tg(Pgr)2Shy/0
Not Specified
abnormal branching of the mammary ductal tree J:45538
abnormal mammary gland duct morphology J:45538
mammary gland duct hyperplasia J:45538
Tg(CMV-GAL4)1Shy/0
Tg(Pgr)3Shy/0
Not Specified
abnormal mammary gland development J:83103
Tsc2tm1.1Mjg/Tsc2tm1.1Mjg
Pgrtm2(cre)Lyd/Pgr+
involves: 129S1/Sv * 129X1/SvJ
abnormal myometrium morphology J:221228
endometrium hyperplasia J:221228
enlarged uterus J:221228
increased endometrial gland number J:221228
increased lung tumor incidence J:221228
increased metastatic potential J:221228
increased uterus leiomyoma incidence J:221228
increased uterus weight J:221228
internal hemorrhage J:221228
Vmn2r53em1Ktou/Vmn2r53+
Pgrtm1.1(cre)Shah/Pgr+
involves: 129S/SvEv * BALB/cCrSlc * C57BL/6J
decreased aggression towards male mice J:327623
Vmn2r53em1Ktou/Vmn2r53em1Ktou
Pgrtm1.1(cre)Shah/Pgr+
involves: 129S/SvEv * BALB/cCrSlc * C57BL/6J
decreased aggression towards male mice J:327623
Wnt7atm1.1Tesp/Wnt7atm1.1Tesp
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
abnormal postimplantation uterine environment J:175291
absent endometrial glands J:175291
female infertility J:175291
Wnt11tm1.1Khay/Wnt11tm1.2Khay
Pgrtm2(cre)Lyd/Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal uterus physiology J:170159
increased endometrial gland number J:170159

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory