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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Abcb4
ATP-binding cassette, sub-family B member 4
MGI:97569
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Abcb4tm1Bor/Abcb4tm1Bor
Pemttm1J/Pemttm1J
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal intestine physiology J:175015
decreased bile salt level J:175015
decreased circulating alanine transaminase level J:175015
increased feces bile salt level J:175015
normal liver/biliary system phenotype J:175015
Abcb4tm1Bor/Abcb4tm1Bor
Portm1Wolf/Portm1Wolf
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N 		abnormal bile salt homeostasis J:215915
bile duct proliferation J:215915
cholestasis J:215915
normal growth/size/body region phenotype J:215915
increased bile salt level J:215915
increased circulating alanine transaminase level J:215915
increased circulating alkaline phosphatase level J:215915
increased circulating bilirubin level J:215915
increased hepatocyte proliferation J:215915
increased liver weight J:215915
liver fibrosis J:215915
Abcb4tm1Bor/Abcb4tm1Bor
Tg(ABCG5/ABCG8)14-2Hobb/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N * SJL 		abnormal bile composition J:100491
abnormal feces composition J:100491
decreased intestinal cholesterol absorption J:100491
normal homeostasis/metabolism phenotype J:100491
increased circulating alanine transaminase level J:100491
increased circulating aspartate transaminase level J:100491
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory