Phb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Phb1
prohibitin 1
MGI:97572

20 phenotypes from 7 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Phb1^em1(IMPC)H/Phb1⁺ C57BL/6NTac-Phb1^em1(IMPC)H/H	decreased circulating potassium level	J:211773
	decreased red blood cell distribution width	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating triglyceride level	J:211773
	increased large unstained cell number	J:211773
Phb1^em1(IMPC)H/Phb1^em1(IMPC)H C57BL/6NTac-Phb1^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Phb1^{Gt(BGB069)Byg}/Phb1⁺ involves: 129P2/OlaHsd * C57BL	abnormal branching of the mammary ductal tree	J:130064
Phb1^{Gt(BGB069)Byg}/Phb1^{Gt(BGB069)Byg} involves: 129P2/OlaHsd * C57BL	embryonic lethality between implantation and somite formation, complete penetrance	J:130064
Phb1^{Gt(OST368818)Lex}/Phb1^{Gt(OST368818)Lex} involves: 129S5/SvEvBrd * C57BL/6J	preweaning lethality, complete penetrance	J:103485
Phb1^{Gt(XT0035)Wtsi}/Phb1⁺ involves: 129P2/OlaHsd * C57BL	abnormal branching of the mammary ductal tree	J:130064
Phb1^{Gt(XT0035)Wtsi}/Phb1^{Gt(XT0035)Wtsi} involves: 129P2/OlaHsd * C57BL	embryonic lethality between implantation and somite formation, complete penetrance	J:130064
Phb1^tm1.1Bwo/Phb1^tm1.1Bwo Pgr^tm2(cre)Lyd/? involves: 129S7/SvEvBrd * C57BL/6	abnormal endometrium morphology	J:173884
	abnormal uterus morphology	J:173884
	abnormal uterus size	J:173884
	decreased uterus weight	J:173884
	normal endocrine/exocrine gland phenotype	J:173884
	endometrium hypoplasia	J:173884
	female infertility	J:173884
	normal homeostasis/metabolism phenotype	J:173884
	thin uterine horn	J:173884
Phb1^tm1.2Bwo/Phb1^tm1.2Bwo involves: 129S7/SvEvBrd * C57BL/6	embryonic lethality, complete penetrance	J:173884
Phb1^tm1Bwo/Phb1^tm1Bwo involves: 129S7/SvEvBrd * C57BL/6	decreased body size	J:173884
Phb1^tm1Bwo/Phb1^tm1Bwo involves: 129S7/SvEvBrd * C57BL/6	prenatal lethality, incomplete penetrance	J:173884

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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