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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
MGI:97583
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kbtbd2em1Btlr/Kbtbd2em1Btlr
Pik3r1em1Btlr/Pik3r1em1Btlr
Not Specified 		decreased circulating glucose level J:236520
decreased circulating insulin level J:236520
increased body fat mass J:236520
increased body weight J:236520
increased insulin sensitivity J:236520
Krastm4Tyj/Kras+
Pik3r1tm1Lca/Pik3r1+
Pik3r2tm1Lca/Pik3r2tm1Lca
involves: 129S4/SvJae * 129S6/SvEvTac 		increased lung tumor incidence J:142254
Krastm4Tyj/Kras+
Pik3r1tm1Lca/Pik3r1tm1Lca
Pik3r2tm1Lca/Pik3r2tm1Lca
involves: 129S4/SvJae * 129S6/SvEvTac 		decreased lung tumor incidence J:142254
Pik3r1tm1Dfr/Pik3r1tm1Dfr
Plcg2tm1Jni/Plcg2tm1Jni
involves: 129P2/OlaHsd * 129S6/SvEvTac 		abnormal B cell differentiation J:104166
arrested B cell differentiation J:104166
decreased body size J:104166
decreased immature B cell number J:104166
decreased mature B cell number J:104166
decreased pre-B cell number J:104166
normal hematopoietic system phenotype J:104166
normal immune system phenotype J:104166
increased B cell apoptosis J:104166
lethality throughout fetal growth and development, complete penetrance J:104166
Pik3r1tm1Lca/Pik3r1tm1Lca
Pik3r2tm1Lca/Pik3r2tm1Lca
Tg(Ckmm-cre)5Khn/0
involves: 129S6/SvEvTac * C57BL/6 * FVB 		decreased heart weight J:102176
decreased myocardial fiber size J:102176
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory