Pkm Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkm
pyruvate kinase, muscle
MGI:97591

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkm^em1(IMPC)Bay/Pkm⁺ C57BL/6N-Pkm^em1(IMPC)Bay/BayMmucd	abnormal embryo size	J:211773
Pkm^em1(IMPC)Bay/Pkm⁺ C57BL/6N-Pkm^em1(IMPC)Bay/BayMmucd	embryonic growth retardation	J:211773
Pkm^em1(IMPC)Bay/Pkm^em1(IMPC)Bay C57BL/6N-Pkm^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Pkm^em1(IMPC)Bay/Pkm^em1(IMPC)Bay C57BL/6N-Pkm^em1(IMPC)Bay/Mmmh	absent egg cylinders	J:279207
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic lethality between implantation and placentation, complete penetrance	J:279207
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
Pkm^r/Pkm^r C57BL/6-Pkm^r	embryonic lethality at implantation, complete penetrance	J:30690
Pkm^r/Pkm^r C57BL/6-Pkm^r	prenatal lethality, complete penetrance	J:6558
Pkm^tm1.1Mgvh/Pkm^tm1.1Mgvh involves: 129S4/SvJaeSor * 129S6/SvEvTac	no abnormal phenotype detected	J:205213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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