Pkm Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pkm
pyruvate kinase, muscle
MGI:97591

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Brca1^tm2Cxd/Brca1^tm2Cxd Pkm^tm1.1Mgvh/Pkm^tm1.1Mgvh Trp53^tm1Brd/Trp53⁺ Tg(MMTV-cre)4Mam/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N	decreased tumor-free survival time	J:205213
	increased liver tumor incidence	J:205213
	increased mammary gland tumor incidence	J:205213
	increased metastatic potential	J:205213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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