Prkacb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkacb
protein kinase, cAMP dependent, catalytic, beta
MGI:97594

8 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkacb^em1(IMPC)H/Prkacb⁺ C57BL/6NTac-Prkacb^em1(IMPC)H/H	increased circulating alanine transaminase level	J:211773
Prkacb^em1(IMPC)H/Prkacb^em1(IMPC)H C57BL/6NTac-Prkacb^em1(IMPC)H/H	preweaning lethality, incomplete penetrance	J:211773
Prkacb^tm1Gsm/Prkacb^tm1Gsm involves: 129X1/SvJ * C57BL/6	absent long-term depression	J:31731
	decreased synaptic depression	J:31731
	reduced long-term potentiation	J:31731
Prkacb^tm2Gsm/Prkacb^tm2Gsm B6.129X1-Prkacb^tm2Gsm	normal behavior/neurological phenotype	J:78451
Prkacb^tm2Gsm/Prkacb^tm2Gsm involves: 129X1/SvJ * C57BL/6	abnormal cued conditioning behavior	J:78451
Prkacb^tm2Gsm/Prkacb^tm2Gsm involves: 129X1/SvJ * C57BL/6	abnormal nervous system physiology	J:78451

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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