Prkca Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkca
protein kinase C, alpha
MGI:97595

13 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkca^tm1Cda/Prkca^tm1Cda involves: 129S/SvEv * C57BL/6	epidermal hyperplasia	J:100793
Prkca^tm1Cda/Prkca^tm1Cda involves: 129S/SvEv * C57BL/6	increased skin papilloma incidence	J:100793
Prkca^tm1Far/Prkca^tm1Far involves: 129/Sv * 129P2/OlaHsd	abnormal enzyme/coenzyme activity	J:85923
	normal homeostasis/metabolism phenotype	J:85923
	increased adipocyte glucose uptake	J:85923
	increased skeletal muscle cell glucose uptake	J:85923
Prkca^tm1Far/Prkca^tm1Far involves: 129P2/OlaHsd	normal nervous system phenotype	J:159855
Prkca^tm1Jmk/Prkca^tm1Jmk involves: 129	abnormal cardiac muscle contractility	J:132098
	abnormal myocardium layer morphology	J:132098
	normal cardiovascular system phenotype	J:88510, J:132098
	decreased response of heart to induced stress	J:88510
Tg(Myh6-Prkca)1Jmk/0 involves: FVB	cardiac hypertrophy	J:88510
Tg(Myh6-Prkca)1Jmk/0 involves: FVB	decreased cardiac muscle contractility	J:88510

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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