Prkcb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkcb
protein kinase C, beta
MGI:97596

18 phenotypes from 8 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkcb^M1Btlr/Prkcb⁺ C57BL/6J-Prkcb^M1Btlr	decreased IgM level	J:164864
Prkcb^M1Btlr/Prkcb^M1Btlr C57BL/6J-Prkcb^M1Btlr	decreased IgM level	J:164864
Prkcb^M1Btlr/Prkcb^M1Btlr involves: C57BL/6J	decreased IgM level	J:185495
Prkcb^M1Btlr/Prkcb^M1Btlr involves: C57BL/6J	normal immune system phenotype	J:185495
Prkcb^M2Btlr/Prkcb⁺ C57BL/6J-Prkcb^M2Btlr	decreased IgM level	J:217791
	decreased response to antigen	J:217791
	impaired humoral immune response	J:217791
Prkcb^M2Btlr/Prkcb^M2Btlr C57BL/6J-Prkcb^M2Btlr	decreased IgM level	J:217791
	decreased response to antigen	J:217791
	impaired humoral immune response	J:217791
Prkcb^M3Btlr/Prkcb⁺ C57BL/6J-Prkcb^M3Btlr	decreased IgM level	J:217793
	decreased response to antigen	J:217793
	impaired humoral immune response	J:217793
Prkcb^M3Btlr/Prkcb^M3Btlr C57BL/6J-Prkcb^M3Btlr	decreased IgM level	J:217793
	decreased response to antigen	J:217793
	impaired humoral immune response	J:217793
Prkcb^M4Btlr/Prkcb^M4Btlr C57BL/6J-Prkcb^M4Btlr	decreased B-1 B cell number	J:274860
	increased CD4-positive, alpha-beta T cell number	J:274860
	increased CD8-positive, alpha-beta T cell number	J:274860
	increased T cell number	J:274860
Prkcb^M5Btlr/Prkcb^M5Btlr C57BL/6J-Prkcb^M5Btlr	decreased IgM level	J:274861
Prkcb^M5Btlr/Prkcb^M5Btlr C57BL/6J-Prkcb^M5Btlr	impaired humoral immune response	J:274861
Prkcb^M6Btlr/Prkcb^M6Btlr C57BL/6J-Prkcb^M6Btlr	decreased B-1 B cell number	J:274862
Prkcb^tilc/Prkcb⁺ involves: C57BL/6JSfdAnu	abnormal humoral immune response	J:221236
	decreased IgG3 level	J:221236
	decreased IgM level	J:221236
Prkcb^tilc/Prkcb^tilc C57BL/6JSfdAnu-Prkcb^tilc/AnuApb	decreased IgM level	J:104190
Prkcb^tilc/Prkcb^tilc involves: C57BL/6JSfdAnu	abnormal humoral immune response	J:221236
	decreased B cell proliferation	J:221236
	decreased B-1a cell number	J:221236
	decreased IgG3 level	J:221236
	decreased IgM level	J:221236
	normal immune system phenotype	J:221236
Prkcb^tm1Tara/Prkcb⁺ involves: 129	abnormal humoral immune response	J:34818
	decreased IgG3 level	J:34818
	decreased IgM level	J:34818
Prkcb^tm1Tara/Prkcb^tm1Tara B6.Cg-Prkcb^tm1Tara	abnormal vascular wound healing	J:106870
Prkcb^tm1Tara/Prkcb^tm1Tara involves: 129	abnormal humoral immune response	J:34818
	decreased B cell number	J:34818
	decreased B cell proliferation	J:34818
	decreased B-1 B cell number	J:34818
	decreased B-1a cell number	J:34818
	decreased IgG3 level	J:34818
	decreased IgM level	J:34818
	normal immune system phenotype	J:34818
Prkcb^tm1Tara/Prkcb^tm1Tara involves: 129 * C57BL/6J	normal nervous system phenotype	J:159855
Prkcb^tm1Tara/Prkcb^tm1Tara involves: C57BL/6	abnormal contextual conditioning behavior	J:77629
	abnormal cued conditioning behavior	J:77629
	normal behavior/neurological phenotype	J:77629
	normal nervous system phenotype	J:77629

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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