Prkcg Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkcg
protein kinase C, gamma
MGI:97597

22 phenotypes from 3 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkcg^em1Jpka/Prkcg⁺ FVB/N-Prkcg^em1Jpka	abnormal gait	J:305637
	abnormal Purkinje cell dendrite morphology	J:305637
	ataxia	J:305637
Prkcg^em1Jpka/Prkcg^em1Jpka FVB/N-Prkcg^em1Jpka	abnormal cerebellar molecular layer	J:305637
	abnormal gait	J:305637
	abnormal innervation	J:305637
	abnormal Purkinje cell dendrite morphology	J:305637
	ataxia	J:305637
	impaired coordination	J:305637
Prkcg^tm1(cre)Zfc/Prkcg^tm1(cre)Zfc involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:100950
Prkcg^tm1Stl/Prkcg^tm1Stl B6.129-Prkcg^tm1Stl	enhanced behavioral response to alcohol	J:54243
Prkcg^tm1Stl/Prkcg^tm1Stl B6;129P2-Prkcg^tm1Stl/J	abnormal excitatory postsynaptic currents	J:159855
Prkcg^tm1Stl/Prkcg^tm1Stl involves: 129P2/OlaHsd * BALB/c	normal behavior/neurological phenotype	J:16391
Prkcg^tm1Stl/Prkcg^tm1Stl involves: 129P2/OlaHsd * C57BL/6	abnormal contextual conditioning behavior	J:16391
	abnormal spatial learning	J:16391
	normal behavior/neurological phenotype	J:16391, J:16392
	normal nervous system phenotype	J:16392
	reduced long-term potentiation	J:16392
Prkcg^tm1Stl/Prkcg^tm1Stl involves: 129S6/SvEvTac * C57BL/6J	abnormal impulsive behavior control	J:79995
	alcohol preference	J:79995
	decreased anxiety-related response	J:64043
	impaired behavioral response to alcohol	J:54243
	normal taste/olfaction phenotype	J:79995
Prkcg^tm1Stl/Prkcg^tm1Stl involves: 129X1/SvJ * C57BL/6J	enhanced behavioral response to alcohol	J:54243
Prkcg^tm1Stl/Prkcg^tm1Stl Not Specified	abnormal nociception after inflammation	J:25061
	abnormal pain threshold	J:25061
	decreased inflammatory response	J:25061
	impaired behavioral response to alcohol	J:25061

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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