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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prkcd
protein kinase C, delta
MGI:97598
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Blnktm1Dkit/Blnktm1Dkit
Prkcdtm1Kin/Prkcdtm1Kin
involves: 129P2/OlaHsd * C57BL/6 * NZB 		abnormal B cell proliferation J:143854
abnormal immunoglobulin level J:143854
abnormal plasma cell differentiation J:143854
arrested B cell differentiation J:143854
decreased B-1 B cell number J:143854
decreased B-2 B cell number J:143854
decreased follicular B cell number J:143854
decreased marginal zone B cell number J:143854
increased B cell apoptosis J:143854
increased IgA level J:143854
increased IgG1 level J:143854
increased IgG2b level J:143854
increased IgG3 level J:143854
increased IgM level J:143854
Prkcdtm1Qxu/Prkcdtm1Qxu
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:76134
Prkcdtm1Qxu/Prkcdtm1Qxu
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell physiology J:76134
abnormal B cell proliferation J:76134
abnormal self tolerance J:76134
abnormal spleen primary B follicle morphology J:76134
autoimmune response J:76134
decreased B cell number J:76134
normal immune system phenotype J:76134
increased spleen germinal center number J:76134
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory