Prkcz Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkcz
protein kinase C, zeta
MGI:97602

17 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkcz^tm1.1Msg/Prkcz^tm1.1Msg involves: 129S6/SvEvTac * C57BL/6J	normal behavior/neurological phenotype	J:194398
	decreased anxiety-related response	J:194398
Prkcz^tm1.1Rlh/Prkcz^tm1.1Rlh Tg(Camk2a-cre/ERT2)2Gsc/0 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	normal nervous system phenotype	J:194557
Prkcz^tm1.2Rlh/Prkcz^tm1.2Rlh either: B6.129-Prkcz^tm1.2Rlh or (involves: 129 * C57BL/6)	normal behavior/neurological phenotype	J:194557
	normal nervous system phenotype	J:194557
Prkcz^{tm1a(EUCOMM)Wtsi}/Prkcz⁺ B6JTyr;B6N-Prkcz^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating iron level	J:175295
Prkcz^{tm1a(EUCOMM)Wtsi}/Prkcz^{tm1a(EUCOMM)Wtsi} B6Brd;B6Dnk;B6N-Tyr^c-Brd Prkcz^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal coat/hair pigmentation	J:232539
Prkcz^{tm1a(EUCOMM)Wtsi}/Prkcz^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Prkcz^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating alanine transaminase level	J:175295
	increased circulating alkaline phosphatase level	J:175295
	increased circulating aspartate transaminase level	J:175295
Prkcz^{tm1a(EUCOMM)Wtsi}/Prkcz^{tm1a(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N	abnormal melanocyte morphology	J:213427
	increased circulating alkaline phosphatase level	J:213427
	persistence of hyaloid vascular system	J:213427
Prkcz^tm1Jmos/Prkcz^tm1Jmos involves: 129P2/OlaHsd * 129/Sv	abnormal Peyer's patch follicle morphology	J:72720
	abnormal Peyer's patch morphology	J:72720
	abnormal spleen marginal zone morphology	J:72720
	decreased B cell number	J:72720
	decreased spleen B cell follicle size	J:72720
	normal immune system phenotype	J:72720
	small Peyer's patches	J:72720

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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