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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Plcg1
phospholipase C, gamma 1
MGI:97615
22 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Plcg1tm1Gcrp/Plcg1tm1Gcrp
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		embryonic growth arrest J:39281
embryonic growth retardation J:39281
embryonic lethality during organogenesis, complete penetrance J:39281
Plcg1tm1Gcrp/Plcg1tm1Rwen
Tg(Cd4-cre)1Cwi/0
either: B6.Cg-Plcg1tm1Gcrp/Plcg1tm1Rwen Tg(Cd4-cre)1Cwi or (involves: 129X1/SvJ * C57BL/6 * DBA/2) 		abnormal T cell activation J:157757
alopecia J:157757
decreased body size J:157757
decreased body weight J:157757
decreased regulatory T cell number J:157757
decreased T cell number J:157757
dermatitis J:157757
ear inflammation J:157757
increased anti-double stranded DNA antibody level J:157757
increased CD4-positive, alpha-beta T cell number J:157757
increased T cell proliferation J:157757
rectal prolapse J:157757
skin inflammation J:157757
Plcg1tm1Ine/Plcg1tm1Ine
involves: 129P2/OlaHsd 		abnormal embryonic hematopoiesis J:73254
embryonic lethality during organogenesis, complete penetrance J:73254
Plcg1tm2Gcrp/Plcg1tm2Gcrp
involves: 129/Sv * CD-1 		abnormal embryonic hematopoiesis J:75316
abnormal proerythroblast morphology J:75316
abnormal vascular endothelial cell development J:75316
abnormal vasculogenesis J:75316
absent visceral yolk sac blood islands J:75316
embryonic lethality during organogenesis, complete penetrance J:75316
Plcg1tm2Gcrp/Plcg1tm2Gcrp
involves: 129S6/SvEvTac * C57BL/6 		embryonic growth arrest J:39281
embryonic growth retardation J:39281
embryonic lethality, complete penetrance J:39281
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory