Plg Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plg
plasminogen
MGI:97620

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Bres/Apoe^tm1Bres Plg^tm1Jld/Plg^tm1Jld involves: 129P2/OlaHsd * C57BL/6 * NIH Black Swiss	abnormal body weight	J:42927
	atherosclerotic lesions	J:42927
	decreased circulating HDL cholesterol level	J:42927
	premature death	J:42927
Cpb2^tm1Efp/Cpb2⁺ Plg^tm1Dco/Plg⁺ involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:80114
	abnormal inflammatory response	J:80114
Cpb2^tm1Efp/Cpb2⁺ Plg^tm1Dco/Plg^tm1Dco involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:80114
Cpb2^tm1Efp/Cpb2^tm1Efp Plg^tm1Dco/Plg⁺ involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:80114
	abnormal inflammatory response	J:80114
Cpb2^tm1Efp/Cpb2^tm1Efp Plg^tm1Dco/Plg^tm1Dco involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:80114
	decreased body size	J:80114
Fga^tm1Jld/Fga^tm1Jld Plg^tm1Jld/Plg^tm1Jld B6.129P2-Fga^tm1Jld Plg^tm1Jld	normal vision/eye phenotype	J:46096
Fga^tm1Jld/Fga^tm1Jld Plg^tm1Jld/Plg^tm1Jld involves: 129P2/OlaHsd	abnormal nervous system physiology	J:42819
Fga^tm1Jld/Fga^tm1Jld Plg^tm1Jld/Plg^tm1Jld involves: 129P2/OlaHsd * Black Swiss * CF-1	abnormal blood coagulation	J:36591
	abnormal duodenum morphology	J:36591
	abnormal liver morphology	J:36591
	abnormal wound healing	J:36591
	focal hepatic necrosis	J:36591
	normal immune system phenotype	J:36591
	normal mortality/aging	J:36591
Ngfr^tm1Jae/Ngfr^tm1Jae Plg^tm1Jld/Plg^tm1Jld involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased body size	J:120368
	hepatic necrosis	J:120368
	increased hepatocyte apoptosis	J:120368
	increased hepatocyte proliferation	J:120368
	premature death	J:120368
Plg^tm1Dco/Plg^tm1Dco Tg(Alb-PLG)1Dgi/0 involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL	decreased body weight	J:120780
	normal liver/biliary system phenotype	J:120780
	normal mortality/aging	J:120780
	rectal prolapse	J:120780
Plg^tm1Jld/Plg⁺ Tg(MSR1-Plau)1Ddi/0 B6.Cg-Plg^tm1Jld Tg(MSR1-Plau)1Ddi	abnormal heart morphology	J:113474
Plg^tm1Jld/Plg^tm1Jld Tg(MMTV-PyVT)634Mul/0 involves: 129P2/OlaHsd * Black Swiss * FVB/N	decreased metastatic potential	J:48285
	increased mammary adenocarcinoma incidence	J:48285

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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