Pnmt Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pnmt
phenylethanolamine-N-methyltransferase
MGI:97724

11 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pnmt^tm1(cre)Sne/Pnmt^tm1(cre)Sne involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased adrenaline level	J:93831
	increased noradrenaline level	J:93831
Pnmt^tm1(cre)Xbao/Pnmt^tm1(cre)Xbao involves: 129X1/SvJ * C57BL/6	abnormal heart size	J:139932
	abnormal systemic arterial blood pressure	J:139932
	normal homeostasis/metabolism phenotype	J:139932
	hypertension	J:139932
	increased noradrenaline level	J:139932
	thick ventricular wall	J:139932
Pnmt^{tm1.1(KOMP)Vlcg}/Pnmt^{tm1.1(KOMP)Vlcg} C57BL/6N-Pnmt^{tm1.1(KOMP)Vlcg}/J	abnormal lens morphology	J:211773
	improved glucose tolerance	J:211773
	increased circulating sodium level	J:211773
Pnmt^tm2.1Sne/Pnmt^tm2.1Sne involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ	no abnormal phenotype detected	J:190425

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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