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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ctsa
cathepsin A
MGI:97748
59 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctsatm1.1Avps/Ctsatm1.1Avps
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal blood vessel elastic tissue morphology J:153297
abnormal cutaneous elastic fiber morphology J:153297
abnormal pulmonary elastic fiber morphology J:153297
abnormal response/metabolism to endogenous compounds J:153297
normal growth/size/body region phenotype J:153297
increased fluid intake J:153297
increased mean systemic arterial blood pressure J:153297
increased systemic arterial diastolic blood pressure J:153297
increased systemic arterial systolic blood pressure J:153297
normal mortality/aging J:153297
overexpanded pulmonary alveolus J:153297
polyuria J:153297
normal reproductive system phenotype J:153297
Ctsatm1Adz/Ctsatm1Adz
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/NJ) 		abnormal lysosome morphology J:29674
ataxia J:29674
decreased body size J:29674
disheveled coat J:29674
edema J:29674
enlarged liver J:29674
enlarged spleen J:29674
flat face J:29674
premature death J:29674
tremors J:29674
Ctsatm1Avps/Ctsatm1Avps
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		normal growth/size/body region phenotype J:153297
normal mortality/aging J:153297
normal reproductive system phenotype J:153297
Ctsatm2b(EUCOMM)Hmgu/Ctsatm2b(EUCOMM)Hmgu
C57BL/6N-Ctsatm2b(EUCOMM)Hmgu/H 		abnormal forelimb morphology J:211773
abnormal freezing behavior J:211773
abnormal gait J:211773
abnormal head morphology J:211773
abnormal hindlimb morphology J:211773
abnormal locomotor behavior J:211773
abnormal startle reflex J:211773
decreased circulating calcium level J:211773
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased circulating triglyceride level J:211773
decreased erythrocyte cell number J:211773
decreased exploration in new environment J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased locomotor activity J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
enlarged spleen J:211773
impaired cued conditioning behavior J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating bilirubin level J:211773
increased circulating iron level J:211773
increased circulating potassium level J:211773
increased freezing behavior J:211773
increased heart weight J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
increased monocyte cell number J:211773
increased spleen weight J:211773
narrow eye opening J:211773
thrombocytopenia J:211773
tremors J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory