Proc Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Proc
protein C
MGI:97771

43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F7^tm1Pec/F7⁺ Proc^tm1Fjc/Proc^tm1Fjc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:61481
	internal hemorrhage	J:61481
	neonatal lethality, complete penetrance	J:61481
F7^tm1Pec/F7^tm1Pec Proc^tm1Fjc/Proc^tm1Fjc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal blood coagulation	J:61481
	abnormal dorsal aorta morphology	J:61481
	hemorrhage	J:61481
	hydrops fetalis	J:61481
	neonatal lethality, complete penetrance	J:61481
F11^tm1Gjb/F11^tm1Gjb Proc^tm1Fjc/Proc^tm1Fjc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiovascular system physiology	J:67398
	abnormal heart morphology	J:67398
	abnormal liver morphology	J:67398
	abnormal lymph circulation	J:67398
	abnormal lymph node cortex morphology	J:67398
	abnormal lymph node morphology	J:67398
	abnormal neutrophil morphology	J:67398
	abnormal pulmonary alveolus morphology	J:67398
	abnormal respiratory system morphology	J:67398
	abnormal respiratory system physiology	J:67398
	abnormal thrombosis	J:67398
	abnormal trachea morphology	J:67398
	anisocytosis	J:67398
	cardiac fibrosis	J:67398
	decreased leukocyte cell number	J:67398
	decreased locomotor activity	J:67398
	decreased neutrophil cell number	J:67398
	enlarged heart	J:67398
	enlarged lymph nodes	J:67398
	gangrene	J:67398
	hepatic necrosis	J:67398
	increased number of Howell-Jolly bodies	J:67398
	increased vascular endothelial cell number	J:67398
	internal hemorrhage	J:67398
	intracranial hemorrhage	J:67398
	liver fibrosis	J:67398
	liver hemorrhage	J:67398
	lung hemorrhage	J:67398
	lung inflammation	J:67398
	lymph node hemorrhage	J:67398
	myocardial fiber degeneration	J:67398
	myocardium necrosis	J:67398
	neonatal lethality, incomplete penetrance	J:67398
	postnatal growth retardation	J:67398
	premature death	J:67398
	respiratory distress	J:67398
	reticulocytosis	J:67398
	thick pulmonary interalveolar septum	J:67398

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24