Ptger1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptger1
prostaglandin E receptor 1 (subtype EP1)
MGI:97793

45 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptger1^tm1Crjk/Ptger1^tm1Crjk B6.129S6-Ptger1^tm1Crjk	abnormal hormone level	J:118519
Ptger1^tm1Crjk/Ptger1^tm1Crjk B6.129S6-Ptger1^tm1Crjk	decreased urine osmolality	J:118519
Ptger1^tm1Dgen/Ptger1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	decreased locomotor activity	J:101679
Ptger1^tm1Jdm/Ptger1^tm1Jdm DBA/1LacJ-Ptger1^tm1Jdm	abnormal nociception after inflammation	J:79387
	decreased systemic arterial blood pressure	J:79387
	normal immune system phenotype	J:72198, J:78964
	increased chemical nociceptive threshold	J:79387
	increased heart rate	J:79387
	increased renin activity	J:79387
	normal mortality/aging	J:79387
	normal reproductive system phenotype	J:79387
Ptger1^tm1Matb/Ptger1^tm1Matb 129S6/SvEvTac-Ptger1^tm1Matb	cardiac hypertrophy	J:127410
	decreased fluid intake	J:127410
	decreased food intake	J:127410
	decreased mean systemic arterial blood pressure	J:127410
	decreased systemic arterial systolic blood pressure	J:127410
	decreased urine sodium level	J:127410
	increased mean systemic arterial blood pressure	J:127410
	oliguria	J:127410
Ptger1^tm1Sna/Ptger1^tm1Sna B6CrSlc.129P2-Ptger1^tm1Sna/Sna	abnormal CD8-positive, alpha-beta T cell differentiation	J:128435
	abnormal cervical lymph node morphology	J:128435
	abnormal impulsive behavior control	J:102926
	abnormal interferon-gamma secretion	J:128435
	abnormal locomotor activation	J:102926
	abnormal lymph node morphology	J:128435
	abnormal response to infection	J:82750
	abnormal social investigation	J:102926
	abnormal T-helper 1 cell differentiation	J:128435
	normal behavior/neurological phenotype	J:102926
	decreased circulating adrenocorticotropin level	J:82750
	decreased dopamine level	J:102926
	decreased susceptibility to type IV hypersensitivity reaction	J:128435
	normal immune system phenotype	J:128435, J:197334
	impaired febrile response	J:105574
	increased aggression towards male mice	J:102926
	increased dopamine level	J:157627
	increased startle reflex	J:102926
Ptger1^tm1Sna/Ptger1^tm1Sna involves: 129P2/OlaHsd	abnormal pain threshold	J:115400
Ptger1^tm1Sna/Ptger1^tm1Sna involves: 129P2/OlaHsd	hyperalgesia	J:115400
Ptger1^tm1Sna/Ptger1^tm1Sna involves: 129P2/OlaHsd * C57BL/6	abnormal physiological response to xenobiotic	J:103150
	normal homeostasis/metabolism phenotype	J:70534
	increased physiological sensitivity to xenobiotic	J:103150
	normal mortality/aging	J:70534
Ptger1^tm1Sna/Ptger1^tm1Sna involves: 129P2/OlaHsd * C57BL/6Cr	abnormal physiological response to xenobiotic	J:95533
	decreased incidence of tumors by chemical induction	J:95533
	decreased tumor growth/size	J:95533
	increased body weight	J:95533
Ptger1^tm1Sna/Ptger1^tm1Sna involves: 129P2/OlaHsd * C57BL/6J	decreased physiological sensitivity to xenobiotic	J:59509

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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