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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptger2
prostaglandin E receptor 2 (subtype EP2)
MGI:97794
38 phenotypes from 6 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptger2tm1.1(KOMP)Vlcg/Ptger2tm1.1(KOMP)Vlcg
C57BL/6N-Ptger2tm1.1(KOMP)Vlcg/Ucd 		female infertility J:211773
male infertility J:211773
Ptger2tm1.1Kand/Ptger2tm1.1Kand
Tg(ITGAM-cre)2781Gkl/0
involves: C57BL/6 * CBA 		abnormal microglial cell physiology J:202677
decreased physiological sensitivity to xenobiotic J:202677
decreased susceptibility to endotoxin shock J:202677
increased physiological sensitivity to xenobiotic J:202677
Ptger2tm1Brey/Ptger2tm1Brey
B6.129S6-Ptger2tm1Brey 		abnormal response to injury J:87388
abnormal spatial learning J:143076
increased cerebral infarct size J:87388
Ptger2tm1Brey/Ptger2tm1Brey
C.129S6-Ptger2tm1Brey 		abnormal excitatory postsynaptic potential J:143076
abnormal microglial cell physiology J:97062
reduced long-term potentiation J:143076
Ptger2tm1Brey/Ptger2tm1Brey
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6) 		abnormal circulating calcium level J:77679
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac 		abnormal vasodilation J:78902
decreased incidence of tumors by chemical induction J:116015
decreased tumor growth/size J:116015
normal homeostasis/metabolism phenotype J:116015
increased vasoconstriction J:78902
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac * BALB/c 		abnormal nervous system physiology J:164638
abnormal response to infection J:164638
Ptger2tm1Brey/Ptger2tm1Brey
involves: 129S6/SvEvTac * C57BL/6 		abnormal airway responsiveness J:103373
abnormal response to infection J:120725
abnormal vasodilation J:53646
decreased litter size J:53646
decreased superovulation rate J:69034
increased systemic arterial blood pressure J:53646
reduced female fertility J:53646
normal reproductive system phenotype J:69034
Ptger2tm1Rsz/Ptger2tm1Rsz
involves: 129S6/SvEvTac * C57BL/6 		abnormal osteoclast differentiation J:77408
Ptger2tm1Sna/Ptger2tm1Sna
B6.129P2-Ptger2tm1Sna/Sna 		normal immune system phenotype J:197334
Ptger2tm1Sna/Ptger2tm1Sna
involves: 129P2/OlaHsd * C57BL/6 		abnormal cumulus expansion J:70534
abnormal oocyte morphology J:57482
absent cumulus expansion J:57482
decreased corpora lutea number J:57482
decreased litter size J:57482
decreased ovulation rate J:57482
normal homeostasis/metabolism phenotype J:70534
impaired fertilization J:57482
normal mortality/aging J:57482
reduced female fertility J:57482
Ptger2tm2Bhk/Ptger2tm2Bhk
involves: 129P2/OlaHsd 		normal cardiovascular system phenotype J:77409
normal renal/urinary system phenotype J:77409
Ptger2tm2Bhk/Ptger2tm2Bhk
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal renin activity J:55713
decreased litter size J:55713
hypotension J:55713
normal immune system phenotype J:78964
impaired fertilization J:55713
reduced female fertility J:55713
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory