Ptger3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptger3
prostaglandin E receptor 3 (subtype EP3)
MGI:97795

21 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptger3^tm1Cof/Ptger3^tm1Cof either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * 129S/SvEv)	abnormal urine osmolality	J:52323
	normal homeostasis/metabolism phenotype	J:52323
	normal mortality/aging	J:52323
Ptger3^tm1Cof/Ptger3^tm1Cof involves: 129P2/OlaHsd	normal cardiovascular system phenotype	J:77409
	decreased renal vascular resistance	J:77409
	increased renal plasma flow rate	J:77409
	increased vasodilation	J:77409
	normal renal/urinary system phenotype	J:77409
Ptger3^tm1Cof/Ptger3^tm1Cof involves: 129P2/OlaHsd * 129S/SvEv	normal immune system phenotype	J:78964
Ptger3^tm1Cof/Ptger3^tm1Cof involves: 129P2/OlaHsd * C57BL/6	decreased susceptibility to induced thrombosis	J:125376
Ptger3^tm1Csml/Ptger3^tm1Csml involves: 129S4/SvJae * C57BL/6	normal homeostasis/metabolism phenotype	J:127396
Ptger3^tm1Csml/Ptger3^tm1Csml involves: 129S4/SvJae * C57BL/6	impaired febrile response	J:127396
Ptger3^tm1Csml/Ptger3^tm1Csml Tg(Nes-cre)1Kln/? involves: 129S4/SvJae * C57BL/6 * SJL	impaired adaptive thermogenesis	J:127396
	impaired febrile response	J:127396
Ptger3^tm1Sna/Ptger3^tm1Sna B6.129P2-Ptger3^tm1Sna/Sna	abnormal body temperature homeostasis	J:105574
	abnormal physiological response to xenobiotic	J:105574
	abnormal response to infection	J:82750
	decreased circulating adrenocorticotropin level	J:82750
	edema	J:197334
	impaired febrile response	J:105574
	increased susceptibility to type I hypersensitivity reaction	J:197334
Ptger3^tm1Sna/Ptger3^tm1Sna involves: 129P2/OlaHsd	abnormal pain threshold	J:115400
	abnormal response/metabolism to endogenous compounds	J:155398
	normal behavior/neurological phenotype	J:115400
	impaired febrile response	J:155398
Ptger3^tm1Sna/Ptger3^tm1Sna involves: 129P2/OlaHsd * C57BL/6	normal homeostasis/metabolism phenotype	J:103150
	impaired febrile response	J:70534
	normal mortality/aging	J:70534
Ptger3^tm1Sna/Ptger3^tm1Sna involves: 129P2/OlaHsd * C57BL/6J	normal homeostasis/metabolism phenotype	J:59509

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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