Pth1r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pth1r
parathyroid hormone 1 receptor
MGI:97801

69 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pth1r^{tm1a(EUCOMM)Hmgu}/Pth1r⁺ C57BL/6N-Pth1r^{tm1a(EUCOMM)Hmgu}/Wtsi	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	increased grip strength	J:211773
	increased total body fat amount	J:211773
Pth1r^{tm1a(EUCOMM)Hmgu}/Pth1r^{tm1a(EUCOMM)Hmgu} C57BL/6N-Pth1r^{tm1a(EUCOMM)Hmgu}/Wtsi	abnormal brain morphology	J:239583
	abnormal ductus venosus valve morphology	J:239583
	abnormal inferior vena cava valve morphology	J:239583
	abnormal lens morphology	J:239583
	abnormal placenta morphology	J:261316
	abnormal thymus morphology	J:239583
	abnormal vertebral artery topology	J:239583
	absent ductus venosus valve	J:239583
	absent segment of posterior cerebral artery	J:239583
	anastomosis between internal carotid artery and basilar artery	J:239583
	blood in lymph vessels	J:239583
	decreased total retina thickness	J:239583
	dilated bile duct	J:239583
	enlarged lymphatic vessel	J:239583
	enlarged paraumbilical vein	J:239583
	herniated liver	J:239583
	increased hemangioma incidence	J:239583
	jugular vein stenosis	J:239583
	placenta hemorrhage	J:239583, J:261316
	preweaning lethality, complete penetrance	J:211773, J:261316
	retropharyngeal edema	J:239583
Pth1r^tm1Abas/Pth1r^tm1Abas B6.Cg-Pth1r^tm1Abas	abnormal blood homeostasis	J:113660
	abnormal circulating phosphate level	J:113660
	abnormal osteoblast physiology	J:113660
	decreased circulating parathyroid hormone level	J:113660
	increased circulating calcium level	J:113660
Pth1r^tm1Hmk/Pth1r^tm1Hmk involves: 129X1/SvJ * Black Swiss * C57BL/6	abnormal bone mineralization	J:34604
	abnormal hyaline cartilage morphology	J:34604
	abnormal long bone epiphyseal plate proliferative zone	J:34604
	abnormal neurocranium morphology	J:34604
	abnormal synchondrosis	J:34604
	atelectasis	J:61316
	decreased embryo size	J:34604, J:61316
	decreased fetal size	J:61316
	decreased length of long bones	J:34604
	domed cranium	J:34604
	embryonic growth retardation	J:61316
	foramen magnum stenosis	J:34604
	neonatal lethality, complete penetrance	J:61316
	perinatal lethality, complete penetrance	J:34604
	protruding tongue	J:34604
	respiratory failure	J:61316
	normal respiratory system phenotype	J:61316
	short limbs	J:34604
	short mandible	J:34604
	short snout	J:34604
	small lung	J:61316
Pth1r^tm1Hmk/Pth1r^tm1Hmk involves: 129X1/SvJ * C57BL/6	decreased embryo size	J:34604
Pth1r^tm1Hmk/Pth1r^tm1Hmk involves: 129X1/SvJ * C57BL/6	lethality throughout fetal growth and development, incomplete penetrance	J:34604
Pth1r^tm1Hmk/Pth1r^tm1Hmk involves: 129X1/SvJ * C57BL/6 * MF1	decreased embryo size	J:34604
	prenatal lethality, incomplete penetrance	J:34604
Pth1r^tm1Hmk/Pth1r^tm2Hmk Tg(Bglap2-cre)1Kry/0 involves: 129S4/SvJae * C57BL/6 * FVB	abnormal long bone epiphyseal plate morphology	J:99641
	increased long bone epiphyseal plate size	J:99641
Pth1r^tm1Hmk/Pth1r^tm3Hmk involves: 129S4/SvJae * C57BL/6	abnormal limb morphology	J:77683
	abnormal long bone epiphyseal plate morphology	J:77683
	abnormal long bone hypertrophic chondrocyte zone	J:77683
	long tibia	J:77683
	postnatal growth retardation	J:77683
	premature chondrocyte differentiation	J:77683
Pth1r^tm2Hmk/Pth1r^tm2Hmk Tg(Bglap2-cre)1Kry/0 involves: 129S4/SvJae * C57BL/6 * FVB	abnormal long bone epiphyseal plate morphology	J:77683
	abnormal long bone hypertrophic chondrocyte zone	J:77683
Pth1r^tm2Hmk/Pth1r^tm2Hmk Tg(Col2a1-cre)1Rsjo/0 involves: 129S4/SvJae * C57BL/6 * FVB/N	abnormal sternum morphology	J:77683
	chondrodystrophy	J:77683
	decreased chondrocyte number	J:77683
	decreased long bone epiphyseal plate size	J:77683
Pth1r^tm2Hmk/Pth1r^tm2Hmk Tg(Dmp1-cre/ERT2)0022Pdp/0 involves: 129S4/SvJae * C3H * C57BL/6	abnormal trabecular bone morphology	J:170229
	decreased bone mineral density of femur	J:170229
	decreased bone mineral density of vertebrae	J:170229
	normal skeleton phenotype	J:170229
Pth1r^tm3Hmk/Pth1r^tm3Hmk involves: 129S4/SvJae * C57BL/6	abnormal long bone epiphyseal plate morphology	J:77683
Pth1r^tm4Hmk/Pth1r^tm4Hmk involves: 129S4/SvJae * C57BL/6	abnormal skeleton development	J:108984

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