Ptprz1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptprz1
protein tyrosine phosphatase receptor type Z, polypeptide 1
MGI:97816

26 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptprz1^{em1(IMPC)Ccpcz}/Ptprz1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Ptprz1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal eye morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	anophthalmia	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	thin skin	J:211773
Ptprz1^tm1Mno/Ptprz1^tm1Mno B6.129-Ptprz1^tm1Mno	abnormal spatial learning	J:98253
	decreased susceptibility to bacterial infection	J:85826
	enhanced long-term potentiation	J:98253
Ptprz1^tm1Mno/Ptprz1^tm1Mno involves: 129S1/Sv * 129X1/SvJ	abnormal contextual conditioning behavior	J:107976
Ptprz1^tm1Mno/Ptprz1^tm1Mno involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:85827
Ptprz1^tm1Schl/Ptprz1^tm1Schl involves: 129	increased osteosarcoma incidence	J:243104
Ptprz1^tm1Schl/Ptprz1^tm1Schl involves: 129 * Swiss Webster	abnormal myelination	J:79860
	abnormal oligodendrocyte morphology	J:79860
	increased susceptibility to experimental autoimmune encephalomyelitis	J:79860
Ptprz1^tm1Vlcg/Ptprz1^tm1Vlcg involves: 129S/SvEvBrd * C57BL/6	abnormal nociception after inflammation	J:148388
	abnormal spatial working memory	J:148388
	normal behavior/neurological phenotype	J:148388
	hypoalgesia	J:148388
	impaired coordination	J:148388
	increased thermal nociceptive threshold	J:148388
	normal nervous system phenotype	J:148388

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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