Qki Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Qki
quaking, KH domain containing RNA binding
MGI:97837

56 phenotypes from 8 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Qki^e5/Qki^e5 B6.101Rl-Qki^e5	abnormal brain white matter morphology	J:102038
	abnormal myelination	J:102038
	abnormal oligodendrocyte morphology	J:102038
	ataxia	J:102038
	premature death	J:102038
	Purkinje cell degeneration	J:102038
	seizures	J:102038
	tremors	J:102038
Qki^e5/Qki^qk-k2 involves: 101/Rl * C57BL/6J * CBA/Ca	normal mortality/aging	J:102038
	seizures	J:102038
	tremors	J:102038
Qki^e5/Qki^qk-kt1 involves: 101/Rl * C57BL/6J	seizures	J:102038
Qki^e5/Qki^qk-kt1 involves: 101/Rl * C57BL/6J	tremors	J:102038
Qki^qk-2J/Qki^qk-2J B6.Cg-Qki^qk-2J/GrsrJ	abnormal myelin sheath morphology	J:97293
	abnormal striatum morphology	J:97293
	postnatal lethality, incomplete penetrance	J:97293
	tremors	J:97293
Qki^qk-2J/Qki^qk-shk involves: 129 * C57BL/6 * C57BLKS/J	tremors	J:220956
Qki^qk-k2/Qki^qk-k2 involves: C57BL/6 * CBA/Ca	abnormal angiogenesis	J:106770
	abnormal anterior visceral endoderm morphology	J:106770
	abnormal developmental patterning	J:27474
	abnormal embryo development	J:27474
	abnormal heart development	J:75828, J:106770
	abnormal heart looping	J:106770
	abnormal nervous system development	J:27474
	abnormal neural plate morphology	J:27474
	abnormal tail development	J:106770
	abnormal vasculogenesis	J:75828
	abnormal visceral yolk sac morphology	J:106770
	abnormal vitelline vasculature morphology	J:75828, J:106770
	absent somites	J:27474
	normal cardiovascular system phenotype	J:75828
	decreased embryo size	J:27474
	decreased vascular endothelial cell number	J:106770
	embryonic growth arrest	J:27474
	embryonic growth retardation	J:106770
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:27474
	embryonic lethality during organogenesis, complete penetrance	J:75828, J:106770
	enlarged heart	J:27474
	normal nervous system phenotype	J:75828
	pericardial effusion	J:75828, J:106770
Qki^qk-k2/Qki^qk-kt1 involves: C57BL/6 * CBA/Ca * STOCK t^w5	embryonic lethality between implantation and placentation, complete penetrance	J:27474
Qki^qk-k2/Qki^qk-kt4 involves: C57BL/6 * CBA/Ca * STOCK t^w5	embryonic growth arrest	J:27474
	perinatal lethality, complete penetrance	J:27474
Qki^qk-kt1/Qki^qk-kt1 involves: STOCK t^w5	abnormal head fold morphology	J:55007
	abnormal heart development	J:55007
	abnormal rostral-caudal axis patterning	J:55007
	abnormal rostral-caudal patterning of the somites	J:55007
	embryonic lethality, complete penetrance	J:55007
Qki^qk-l1/Qki^qk-l1 involves: BTBR	abnormal angiogenesis	J:106770
	abnormal anterior visceral endoderm morphology	J:106770
	abnormal heart development	J:106770
	abnormal heart looping	J:106770
	abnormal tail development	J:106770
	abnormal vitelline vasculature morphology	J:106770
	embryonic growth retardation	J:106770
	embryonic lethality during organogenesis, complete penetrance	J:106770
	pericardial effusion	J:106770
Qki^qk-shk/Qki^qk-shk involves: 129 * C57BL/6	abnormal paranode morphology	J:220956
	normal behavior/neurological phenotype	J:220956
	decreased myelin sheath thickness	J:220956
	demyelination	J:220956
	impaired coordination	J:220956
	short stride length	J:220956
	tonic seizures	J:220956
	tremors	J:220956
Qki^tm1Imeg/Qki^tm1Imeg involves: 129P2/OlaHsd	abnormal blood vessel morphology	J:88215
	abnormal heart morphology	J:88215
	abnormal hematopoietic system morphology/development	J:88215
	abnormal myocardium layer morphology	J:88215
	abnormal neural tube morphology	J:88215
	abnormal vitelline vasculature morphology	J:88215
	decreased embryo size	J:88215
	embryonic lethality during organogenesis, complete penetrance	J:88215
	incomplete embryo turning	J:88215
	open neural tube	J:88215
	pericardial effusion	J:88215
	wavy neural tube	J:88215

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24