Eprs1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eprs1
glutamyl-prolyl-tRNA synthetase 1
MGI:97838

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eprs1^tm1.1Xen/Eprs1^tm1.1Xen C57BL/6-Eprs1^tm1.1Xen	abnormal adipose tissue physiology	J:244749
	decreased abdominal adipose tissue amount	J:244749
	decreased body weight	J:244749
	decreased brown adipose tissue amount	J:244749
	decreased susceptibility to diet-induced obesity	J:244749
	decreased white fat cell size	J:244749
	enhanced lipolysis	J:244749
	extended life span	J:244749
	normal homeostasis/metabolism phenotype	J:244749
	impaired glucose tolerance	J:244749
	increased carbon dioxide production	J:244749
	increased energy expenditure	J:244749
	increased fatty acid beta-oxidation	J:244749
	increased insulin sensitivity	J:244749
	increased oxygen consumption	J:244749
Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1⁺ C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal embryo size	J:211773
	abnormal lung morphology	J:211773
	decreased prepulse inhibition	J:211773
Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Eprs1^tm2.1Xen/Eprs1^tm2.1Xen C57BL/6-Eprs1^tm2.1Xen	no abnormal phenotype detected	J:244749

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24