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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rag1
recombination activating 1
MGI:97848
200 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Bcl6btm2Dent/Bcl6btm2Dent
Rag1tm1Mom/Rag1tm1Mom
involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 		abnormal blood cell morphology/development J:123621
decreased lymphocyte cell number J:123621
C1galt1ptl1/C1galt1ptl1
Rag1tm1Bal/Rag1tm1Bal
involves: 129S4/SvJae * C57BL/6 		abnormal kidney morphology J:115272
abnormal renal tubule morphology J:115272
decreased renal glomerulus number J:115272
increased mean platelet volume J:115272
increased urine protein level J:115272
kidney inflammation J:115272
premature death J:115272
thrombocytopenia J:115272
Cd79atm2(cre/Esr1*)Reth/Cd79a+
Rag1tm1.1Sadu/Rag1tm1.1Sadu
involves: BALB/c 		arrested B cell differentiation J:155473
Cd160tm1Yxf/Cd160tm1Yxf
Rag1tm1Mom/Rag1tm1Mom
B6.Cg-Rag1tm1Mom Cd160tm1Yxf 		decreased interferon-gamma secretion J:222131
increased tumor growth/size J:222131
Clec2htm1.1Apma/Clec2htm1.1Apma
Rag1tm1Mom/Rag1tm1Mom
B6.Cg-Rag1tm1Mom Clec2htm1.1Apma 		abnormal adipose tissue amount J:322835
abnormal kidney capillary morphology J:322835
abnormal renal glomerulus morphology J:322835
decreased body weight J:322835
glomerular crescent J:322835
glomerulosclerosis J:322835
increased mesangial cell number J:322835
kidney inflammation J:322835
renal glomerulus fibrosis J:322835
renal interstitial fibrosis J:322835
renal tubule atrophy J:322835
Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+
Rag1tm1Fwa/Rag1tm1Fwa
chimera involves: C57BL/6 * C57BL/6N 		abnormal B cell physiology J:207033
abnormal B-1a B cell morphology J:207033
decreased B cell proliferation J:207033
decreased B-1a cell number J:207033
decreased IgG2b level J:207033
decreased IgM level J:207033
decreased plasma cell number J:207033
Col1a1tm1(tetO-Fos)Wag/Col1a1+
Rag1tm1Mom/Rag1tm1Mom
Tg(KRT5-rtTA)T2D6Sgkd/0
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N 		normal integument phenotype J:201145
skin hyperplasia J:201145
skin lesions J:201145
Ctla4tm1All/Ctla4tm1All
Rag1tm1Mom/Rag1tm1Mom
Tg(TcrAND)53Hed/0
involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal T cell activation J:119845
increased interleukin-4 secretion J:119845
increased T cell proliferation J:119845
Ctla4tm1All/Ctla4tm1All
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)8Rest/0
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 		normal immune system phenotype J:140448
normal mortality/aging J:140448
normal pigmentation phenotype J:140448
Ctps1tm1c(KOMP)Wtsi/Ctps1tm1c(KOMP)Wtsi
Tg(Cd4-cre)1Cwi/0
Foxp3sf/Y
Rag1tm1Mom/Rag1+
mixed 		decreased body weight J:348981
decreased inflammatory response J:348981
decreased regulatory T cell number J:348981
decreased T cell proliferation J:348981
enlarged spleen J:348981
thymus hypoplasia J:348981
Ewsr1tm1(ERG)Thr/Ewsr1+
Rag1tm1(cre)Thr/Rag1+
involves: 129S/SvEv 		increased leukemia incidence J:98679
increased lymphocyte cell number J:98679
increased T cell derived lymphoma incidence J:98679
Foxo1tm1Flv/Foxo1tm1Flv
Rag1tm1Mom/Rag1tm1Mom
Tg(CD2-Il7r)1Asin/?
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 		decreased T cell number J:147057
Foxo1tm1Flv/Foxo1tm1Flv
Rag1tm1Mom/Rag1tm1Mom
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 		decreased T cell number J:147057
Foxp3tm1.1Ayr/Y
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)425Cbn/0
Not Specified 		normal immune system phenotype J:97029
no abnormal phenotype detected J:97029
Gt(ROSA)26Sortm1(DTA)Lky/?
Il5tm1.1(icre)Lky/Il5+
Rag1tm1Mom/Rag1tm1Mom
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal immune system physiology J:206097
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Rag1tm1Mom/Rag1tm1Mom
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
NOD.Cg-Rag1tm1Mom H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell 		abnormal response to transplant J:113267
normal cardiovascular system phenotype J:113267
enlarged heart J:113267
heart inflammation J:113267
increased autoantibody level J:113267
myocarditis J:113267
prolonged PR interval J:113267
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DQA1,HLA-DQB1)73Myl/0
NOD.Cg-Rag1tm1Mom H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)73Myl 		abnormal response to transplant J:88055
myocarditis J:88055
H2b/H2b
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra19,Tcrb19)#Stl/0
involves: 129S7/SvEvBrd * C57BL/6 		normal immune system phenotype J:19795
H2dlAb1-Ea/H2dlAb1-Ea
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 		brain inflammation J:189816
H2dlAb1-Ea/H2dlAb1-Ea
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DRA,HLA-DRB5*0101)loKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 		brain inflammation J:189816
H2g7/H2g7
Ins2tm1Jja/Ins2tm1Jja
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD 		increased circulating glucose level J:111874
increased susceptibility to autoimmune diabetes J:111874
H2g7/H2g7
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD 		increased susceptibility to autoimmune diabetes J:111874
insulitis J:111874
H2g7/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD 		increased susceptibility to autoimmune diabetes J:111874
H2q/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD 		decreased susceptibility to autoimmune diabetes J:111874
normal digestive/alimentary phenotype J:111874
H2u/H2u
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra19,Tcrb19)#Stl/0
either: (involves: 129S7/SvEvBrd * C57BL/6 * PL/J) or (involves: 129S7/SvEvBrd * C57BL/6 * C57BL/10 * PL/J) 		increased susceptibility to autoimmune disorder J:19795
limb paralysis J:19795
Ier3tm1Mxw/Ier3tm1Mxw
Rag1tm1Mom/Rag1tm1Mom
involves: 129S7/SvEvBrd * C57BL/6 		decreased susceptibility to induced colitis J:194587
Igh-Jtm1Mcdl/Igh-Jtm1Mcdl
Igk-Jtm1Mcdl/Igk-Jtm1Mcdl
Rag1tm1Mom/Rag1tm1Mom
Tg(DO11.10)10Dlo/?
involves: 129S/Sv * BALB/c * C3H * C57BL/6 		abnormal spleen germinal center morphology J:100072
abnormal T cell differentiation J:100072
increased IgE level J:100072
increased IgG level J:100072
Il2rgtm1Wjl/Y
Rag1tm1Mom/Rag1tm1Mom
NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ 		abnormal adaptive immunity J:140388
abnormal innate immunity J:140388
abnormal response to transplant J:140388
abnormal spleen morphology J:140388
abnormal thymus morphology J:140388
absent NK T cells J:140388
absent thymus cortex J:140388
absent thymus medulla J:140388
decreased macrophage cell number J:140388
decreased spleen B cell follicle number J:140388
thymus cyst J:140388
Inpp5dtm1Rkh/Inpp5dtm1Rkh
Rag1tm1(GFP)Imku/Rag1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal lymphopoiesis J:117320
Ins2Akita/Ins2+
Prf1tm1Sdz/Prf1tm1Sdz
Rag1tm1Mom/Rag1tm1Mom
NOD.Cg-Rag1tm1Mom Ins2Akita Prf1tm1Sdz 		abnormal glucose homeostasis J:138005
abnormal pancreatic islet morphology J:138005
absent mature B cells J:138005
absent T cells J:138005
normal homeostasis/metabolism phenotype J:138005
hyperglycemia J:138005
increased erythrocyte cell number J:138005
increased granulocyte number J:138005
increased macrophage cell number J:138005
increased monocyte cell number J:138005
Ins2Akita/Ins2Akita
Prf1tm1Sdz/Prf1tm1Sdz
Rag1tm1Mom/Rag1tm1Mom
NOD.Cg-Rag1tm1Mom Ins2Akita Prf1tm1Sdz 		postnatal lethality, complete penetrance J:138005
Itktm1Ljb/Itktm1Ljb
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra5CC7,Tcrb5CC7)IWep/?
involves: 129 * C57BL/10 		abnormal CD4-positive T cell differentiation J:93606
decreased interferon-gamma secretion J:93606
decreased interleukin-4 secretion J:93606
decreased interleukin-5 secretion J:93606
decreased interleukin-10 secretion J:93606
Jak3tm1Ljb/Jak3tm1Ljb
Rag1tm1Mom/Rag1tm1Mom
involves: 129S4/SvJae * 129S7/SvEvBrd 		abnormal splenic cell ratio J:56629
normal immune system phenotype J:56629
Lattm1.1Mal/Lattm1.1Mal
Rag1tm1Bal/Rag1tm1Bal
involves: 129S2/SvPas * 129S4/SvJae 		abnormal platelet dense granule physiology J:125744
decreased platelet aggregation J:125744
Lattm2.1Mal/Lattm2.1Mal
Rag1tm1Bal/Rag1tm1Bal
involves: 129S2/SvPas * 129S4/SvJae 		abnormal platelet dense granule physiology J:125744
abnormal thrombosis J:125744
decreased platelet aggregation J:125744
Lcktm1Mak/Lcktm1Mak
Rag1tm1Mom/Rag1+
Tg(Lck-Fyn*Y528F)5525Cjg/0
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 		abnormal T cell differentiation J:37062
decreased T cell number J:37062
Lmo2tm3Thr/Lmo2tm4Thr
Rag1tm1(cre)Thr/Rag1+
involves: 129S/SvEv 		normal hematopoietic system phenotype J:86869
normal immune system phenotype J:86869
Man2a1tm1Jxm/Man2a1tm1Jxm
Rag1tm1Mom/Rag1tm1Mom
B6.129-Rag1tm1Mom Man2a1tm1Jxm 		abnormal nephron morphology J:124348
alopecia J:124348
increased mesangial cell apoptosis J:124348
increased urine protein level J:124348
kidney inflammation J:124348
weight loss J:124348
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
Rag1tm1Mom/Rag1tm1Mom
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 		abnormal cytokine secretion J:172117
decreased body weight J:172117
increased circulating interleukin-1 beta level J:172117
increased circulating interleukin-6 level J:172117
increased circulating tumor necrosis factor level J:172117
increased inflammatory response J:172117
increased interferon-gamma secretion J:172117
increased interleukin-1 beta secretion J:172117
increased interleukin-2 secretion J:172117
increased interleukin-4 secretion J:172117
increased interleukin-5 secretion J:172117
increased interleukin-9 secretion J:172117
increased interleukin-10 secretion J:172117
increased interleukin-12 secretion J:172117
increased interleukin-13 secretion J:172117
increased interleukin-17 secretion J:172117
Mpztm1Msch/Mpz+
Rag1tm1Mom/Rag1tm1Mom
B6.129S7-Mpztm1Msch Rag1tm1Mom 		abnormal myelin sheath morphology J:59319
abnormal myelination J:59319
abnormal nerve conduction J:59319
abnormal neuron morphology J:59319
absent CD4-positive, alpha-beta T cells J:59319
absent CD8-positive, alpha-beta T cells J:59319
increased Schwann cell number J:59319
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)425Cbn/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * BALB/c * C57BL/6 		normal immune system phenotype J:205692
Nfil3tm1Pbro/Nfil3tm1Pbro
Rag1tm1Mom/Rag1tm1Mom
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 		normal immune system phenotype J:209365
Nlrp3tm1Hhf/Nlrp3+
Rag1tm1Mom/Rag1tm1Mom
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		absent B cells J:150054
absent T cells J:150054
postnatal lethality, complete penetrance J:150054
reddish skin J:150054
scaly skin J:150054
slow postnatal weight gain J:150054
Pdpntm2.1Mlkn/Pdpntm2.1Mlkn
Rag1tm1Mom/Rag1tm1Mom
Tg(Pdgfrb-cre)9Rha/0
involves: 129S7/SvEvBrd * C57BL/6 		absent lymphocyte J:205423
normal cardiovascular system phenotype J:205423
Plcg2Ali5/Plcg2+
Rag1tm1Mom/Rag1tm1Mom
involves: 129S7/SvEvBrd * C3HeB/FeJ * C3HeB/FeJ-Plcg2Ali5 		chronic inflammation J:97930
dermatitis J:97930
osteoarthritis J:97930
Pld4tm1.2Nemz/Pld4tm1.2Nemz
Rag1tm1Mom/Rag1tm1Mom
involves: 129 * 129S7/SvEvBrd * C57BL/6J * FVB/N 		abnormal peritoneal macrophage morphology J:281205
decreased NK T cell number J:281205
Prf1tm1Sdz/Prf1tm1Sdz
Rag1tm1Mom/Rag1tm1Mom
NOD.Cg-Rag1tm1Mom Prf1tm1Sdz/SzJ 		abnormal response to transplant J:91764
increased circulating glucose level J:91764
Pstpip2Lupo/Pstpip2Lupo
Rag1tm1Mom/Rag1tm1Mom
involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J 		skin inflammation J:125785
Rag1tm1(cre)Thr/?
Shcbp1tm1c(EUCOMM)Wtsi/Shcbp1tm1c(EUCOMM)Wtsi
involves: C57BL/6N 		normal immune system phenotype J:212898
Rag1tm1(GFP)Imku/?
Zfp335blt/Zfp335blt
involves: C57BL/6 * CBA 		abnormal CD4-positive T cell differentiation J:214793
Rag1tm1.1Sadu/Rag1tm1.1Sadu
Trdctm1Mal/Trdctm1Mal
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		absent gamma-delta T cells J:187400
decreased gamma-delta T cell number J:187400
increased gamma-delta T cell number J:187400
small thymus J:187400
Rag1tm1Bal/Rag1tm1Bal
Tg(TcraTcrb)1100Mjb/?
involves: 129S4/SvJae * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:133645
decreased CD4-positive, alpha-beta T cell number J:133645
increased CD8-positive, alpha-beta T cell number J:133645
Rag1tm1Bal/Rag1tm1Bal
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl
involves: 129/Sv * C57BL/6 		liver inflammation J:92470
Rag1tm1Bal/Rag1tm1Bal
Vav1tm2Tyb/Vav1tm2Tyb
involves: 129S4/SvJae * 129S8/SvEv 		arrested T cell differentiation J:113270
Rag1tm1Bal/Rag1tm1Bal
Vav1tm2Tyb/Vav1tm2Tyb
Tg(TcrAND)53Hed/0
involves: 129S4/SvJae * 129S8/SvEv * C57BL/6 * SJL 		decreased CD4-positive, alpha-beta T cell number J:113270
Rag1tm1Fwa/Rag1tm1Fwa
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129S6/SvEvTac 		normal cellular phenotype J:170462
Rag1tm1Jsek/Rag1tm1Jsek
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129S6/SvEvTac 		decreased survivor rate J:146912
increased T cell derived lymphoma incidence J:146912
premature death J:146912
spontaneous chromosome breakage J:146912
Rag1tm1Mom/Rag1+
Tg(LPV-TAg1135)11Tvd/0
involves: 129/Sv * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag1tm1Mom/Rag1+
Tg(LPV-TAg1135)11Tvd/0
Tg(TcrLCMV)327Sdz/0
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag1tm1Mom/Rag1tm1Mom
Prf1tm1Sdz/Prf1tm1Sdz
NOD.Cg-Rag1tm1Mom Prf1tm1Sdz/Sz 		abnormal level of surface class II molecules J:109843
abnormal lymph node cortex morphology J:109843
abnormal response to transplant J:109843
abnormal spleen white pulp morphology J:109843
abnormal thymus cortex morphology J:109843
decreased CD4-positive, alpha-beta T cell number J:109843
decreased CD8-positive, alpha-beta T cell number J:109843
decreased immunoglobulin level J:109843
decreased mature B cell number J:109843
impaired natural killer cell mediated cytotoxicity J:109843
increased granulocyte number J:109843
increased immature B cell number J:109843
increased macrophage cell number J:109843
increased NK cell number J:109843
increased T cell derived lymphoma incidence J:109843
premature death J:109843
spleen hypoplasia J:109843
thymus hypoplasia J:109843
Rag1tm1Mom/Rag1tm1Mom
Rasa3scat/Rasa3scat
involves: 129S7/SvEvBrd * BALB/cBy 		abnormal hematopoietic system morphology/development J:186485
abnormal immune system morphology J:186485
Rag1tm1Mom/Rag1tm1Mom
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro
involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/cJ * C57BL/6J 		abnormal osteoclast differentiation J:117880
decreased bone mineral density J:117880
increased circulating tumor necrosis factor level J:117880
increased inflammatory response J:117880
Rag1tm1Mom/Rag1tm1Mom
Slc46a2tm1Moki/Slc46a2+
Tg(TcraB12,TcrbB12)1Rest/0
involves: 129 * C57BL/6 		arrested T cell differentiation J:140121
decreased double-positive T cell number J:140121
increased T cell apoptosis J:140121
thymus hypoplasia J:140121
Rag1tm1Mom/Rag1tm1Mom
Tg(CAG-Lyn*)#Paau/0
involves: 129S7/SvEvBrd * C57BL/6 		decreased inflammatory response J:151886
Rag1tm1Mom/Rag1tm1Mom
Tg(Lck-Akt1*E40K)E-3Pnt/0
involves: 129S7/SvEvBrd * C3H/He * C57BL/6 		increased double-positive T cell number J:135903
increased thymocyte number J:135903
Rag1tm1Mom/Rag1tm1Mom
Tg(LPV-TAg1135)11Tvd/0
involves: 129/Sv * C57BL/6 * DBA/2 		abnormal T cell receptor V(D)J recombination J:47667
increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag1tm1Mom/Rag1tm1Mom
Tg(LPV-TAg1135)11Tvd/0
Tg(TcrLCMV)327Sdz/0
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra,Tcrb)HRCAll/0
B6.Cg-Rag1tm1Mom Tg(Tcra,Tcrb)HRCAll 		abnormal T cell differentiation J:131347
abnormal T cell subpopulation ratio J:131347
absent CD4-positive, alpha-beta T cells J:131347
increased CD8-positive, alpha-beta T cell number J:131347
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0
NOD.Cg-Rag1tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs 		increased susceptibility to autoimmune diabetes J:94192
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD 		decreased CD4-positive, alpha-beta T cell number J:111874
decreased lymphocyte cell number J:111874
decreased pancreatic beta cell number J:111874
decreased thymus weight J:111874
increased circulating glucose level J:111874
increased double-positive T cell number J:111874
increased susceptibility to autoimmune diabetes J:111874
Rag1tm1Mom/Rag1tm1Mom
Tnftm2Gkl/Tnf+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		rheumatoid arthritis J:54056
small intestinal inflammation J:54056
Rag1tm1Mom/Rag1tm1Mom
Tnfrsf25tm1Mjo/Tnfrsf25tm1Mjo
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal T cell differentiation J:84536
Rag1tm1Mom/Rag1tm1Mom
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal trabecular bone morphology J:294030
decreased osteoclast cell number J:294030
increased osteoblast cell number J:294030
Rag1tm1Mom/Rag1tm1Mom
Trp53tm1Brd/Trp53tm1Brd
involves: 129S7/SvEvBrd * C57BL 		dehydration J:141515
impaired balance J:141515
increased hemangiosarcoma incidence J:141515
increased hepatocellular carcinoma incidence J:141515
increased medulloblastoma incidence J:141515
increased pituitary adenoma incidence J:141515
increased sarcoma incidence J:141515
increased T cell derived lymphoma incidence J:141515
premature death J:141515
respiratory distress J:141515
Rag1tm1Mom/Rag1tm1Mom
Trp53tm1Brd/Trp53tm1Brd
Xrcc5tm1Dbr/Xrcc5tm1Dbr
involves: 129S7/SvEvBrd * C57BL 		dehydration J:141515
impaired balance J:141515
increased medulloblastoma incidence J:141515
increased sarcoma incidence J:141515
increased stomach tumor incidence J:141515
increased T cell derived lymphoma incidence J:141515
premature death J:141515
respiratory distress J:141515
Rag1tm1Mom/Rag1tm1Mom
Tyrobptm1.1Viv/Tyrobptm1.1Viv
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/10 		abnormal bone remodeling J:129304
abnormal osteoclast physiology J:129304
increased bone mass J:129304
increased bone trabecula number J:129304
increased trabecular bone connectivity density J:129304
osteopetrosis J:129304
Rag1tm1Mom/Rag1tm1Mom
Tyrp1B-w/Tyrp1B-w
X/Tg(Tcra,Tcrb)9Rest
involves: 101/Rl * 129S7/SvEvBrd * C3H/Rl * C57BL/6 		abnormal tumor susceptibility J:138466
Rag1tm1Mom/Rag1tm1Mom
Vtcn1tm1Lpc/Vtcn1tm1Lpc
involves: 129S/SvEvBrd * 129S7/SvEvBrd * C57BL/6 		abnormal neutrophil differentiation J:145712
decreased susceptibility to bacterial infection J:145712
decreased susceptibility to bacterial infection induced morbidity/mortality J:145712
increased neutrophil cell number J:145712
increased spleen weight J:145712
Rag1tm1Mom/Rag1tm1Mom
Xrcc5tm1Dbr/Xrcc5tm1Dbr
involves: 129S7/SvEvBrd * C57BL 		increased cerebellar granule cell number J:141515
normal neoplasm J:141515
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory