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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rag2
recombination activating gene 2
MGI:97849
134 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Rag2tm1Fwa/Rag2+
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal aorta morphology J:59156
decreased body weight J:59156
decreased circulating cholesterol level J:59156
decreased circulating HDL cholesterol level J:59156
increased uterus weight J:59156
Apoetm1Unc/Apoetm1Unc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal aorta morphology J:59156
decreased body weight J:59156
decreased circulating cholesterol level J:59156
decreased circulating HDL cholesterol level J:59156
increased uterus weight J:59156
Cbltm1.1Hua/Cbltm1.1Hua
Lcp2tm1Gak/Lcp2tm1Gak
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ 		abnormal T cell differentiation J:91369
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv 		increased T cell proliferation J:88120
Cd8atm1Asin/Cd8atm1Asin
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J 		abnormal CD8-positive, alpha beta T cell morphology J:125259
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * BALB/cAnNTac 		abnormal immune system physiology J:177073
normal craniofacial phenotype J:177073
normal hematopoietic system phenotype J:177073
normal immune system phenotype J:177073
normal skeleton phenotype J:177073
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac 		abnormal response to transplant J:168302
Ctcftm2Gal/Ctcftm2Gal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-cre)1Cwi/0
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10 		decreased double-positive T cell number J:143271
Ctla4tm1Shr/Ctla4tm1Shr
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0
involves: 129S/Sv * BALB/c * C3H * C57BL/6 		abnormal cytokine secretion J:110446
abnormal T cell physiology J:110446
normal immune system phenotype J:110446
Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa
involves: C57BL/6J * C57BL/6NTac 		abnormal response to transplant J:290663
Dnajc11spc/Dnajc11spc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S6/SvEvTac * C57BL/6J 		normal abnormal behavior J:221543
Dusp5tm1.1Achn/Dusp5tm1.1Achn
Rag2tm1.1Cgn/Rag2tm1.1Cgn
involves: C57BL/6NCrl 		abnormal eosinophil physiology J:218203
abnormal susceptibility to parasitic infection J:218203
increased eosinophil cell number J:218203
Erap1tm1Luc/Erap1tm1Luc
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrLCMV)327Sdz/Tg(TcrLCMV)327Sdz
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * C57BL/10SgSnAi * DBA/2 		normal immune system phenotype J:122479
Errfi1tm1Gvw/Errfi1tm1Gvw
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv 		osteoarthritis J:100927
Gata3tm1Jfz/Gata3tm1Jfz
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-cre)1Cwi/0
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		abnormal T cell differentiation J:141145
Gpr15tm1.1Litt/Gpr15tm1.1Litt
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraTcrb)425Cbn/0
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 		abnormal immune system physiology J:199126
H2b/H2b
Nfkbidtm1Clay/Nfkbidtm1Clay
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 		abnormal thymocyte activation J:132071
decreased interleukin-2 secretion J:132071
decreased T cell proliferation J:132071
H2b/H2b
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6 		abnormal cytotoxic T cell physiology J:133112
arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
increased CD8-positive, alpha-beta T cell number J:133112
increased T cell proliferation J:133112
H2d/H2d
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6 		arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
decreased CD8-positive, alpha-beta T cell number J:133112
Hgftm1Jmw/Hgftm1Jmw
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased hepatocyte proliferation J:97145
impaired liver regeneration J:97145
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
Cd79atm1(cre)Reth/Cd79a+
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL 		decreased pro-B cell number J:209928
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal intestinal epithelium morphology J:29999
abnormal intestinal goblet cell morphology J:29999
anemia J:29999
cachexia J:29999
colitis J:29999
diarrhea J:29999
enlarged mesenteric lymph nodes J:29999
hunched posture J:29999
rectal hemorrhage J:29999
rectal prolapse J:29999
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal blood cell morphology/development J:29999
normal immune system phenotype J:29999
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129P2/OlaHsd * C57BL/10 		abnormal T cell number J:120176
increased T-helper 17 cell number J:120176
Il2rbtm1Mak/Il2rbtm1Mak
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129 * 129S/SvEv 		decreased NK cell number J:142654
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac 		abnormal response to transplant J:168302
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168301
thrombocytopenia J:168301
Il2rgtm1.1Flv/Y
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
Il2rgtm1Cgn/Il2rgtm1Cgn
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal interleukin secretion J:142654
decreased NK cell number J:142654
increased susceptibility to bacterial infection J:142654
Il2rgtm1Cgn/Y
Rag2tm1Fwa/Rag2tm1Fwa
B6.129-Rag2tm1Fwa Il2rgtm1Cgn 		absent B cells J:132257
absent NK cells J:132257
absent T cells J:132257
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S4/SvJae 		abnormal interferon secretion J:140483
absent NK cells J:140483
absent T cells J:140483
increased susceptibility to bacterial infection J:140483
increased susceptibility to induced morbidity/mortality J:140483
lung inflammation J:140483
Il6sttm1Thir/Il6sttm1Thir
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		normal immune system phenotype J:133059
Il7tm1Dnax/Il7tm1Dnax
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		decreased NK cell number J:132257
Il12atm1Jm/Il12atm1Jm
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129S6/SvEvTac 		abnormal interferon secretion J:140483
decreased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Il12btm1Jm/Il12btm1Jm
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv 		abnormal chemokine secretion J:140483
abnormal interferon secretion J:140483
increased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Il15tm1Imx/Il15tm1Imx
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		decreased NK cell number J:132257
Il23rtm1.1Ngh/Il23rtm1.1Ngh
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		abnormal circulating interleukin level J:216867
abnormal large intestine crypts of Lieberkuhn morphology J:216867
decreased colon length J:216867
decreased interleukin-17 secretion J:216867
weight loss J:216867
Lattm6.1(HBEGF/EGFP)Mal/?
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal T cell physiology J:138401
Lime1tm1.1Mal/Lime1tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
B6.Cg-Rag2tm1Fwa Lime1tm1.1Mal Tg(TcraH-Y,TcrbH-Y)1Pas 		abnormal CD4-positive T cell differentiation J:126321
increased CD4-positive, alpha-beta T cell number J:126321
Mmp9tm1Tvu/Mmp9tm1Tvu
Rag2tm1Fwa/Rag2tm1Fwa
B6.129S-Rag2tm1Fwa Mmp9tm1Tvu 		decreased tumor incidence J:105098
Mmp9tm1Tvu/Mmp9tm1Tvu
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * FVB/N 		abnormal tumor morphology J:140033
decreased metastatic potential J:140033
decreased tumor growth/size J:140033
Mogtm1Dpd/Mogtm1Dpd
Rag2tm1Cgn/Rag2tm1Cgn
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Nfkbiztm1Aki/Nfkbiztm1Aki
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		normal immune system phenotype J:194832
Nr3c1tm1.1Jda/Nr3c1tm1.1Jda
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(Lck-cre)548Jxm/0
Tg(TcrAND)53Hed/0
B6.Cg-Rag2tm1.1Cgn Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm Tg(TcrAND)53Hed 		decreased double-positive T cell number J:189951
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw
Rag2tm1Fwa/Rag2tm1Fwa
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
involves: 129S/SvEv * 129X1/SvJ * C57BL/6 		abnormal keratinocyte differentiation J:226194
dermatitis J:226194
epidermal hyperplasia J:226194
premature death J:226194
Prss16tm1.1Mal/Prss16+
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
Prss16tm1.1Mal/Prss16tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased double-positive T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
spleen hypoplasia J:148034
thymus hypoplasia J:148034
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2 		autoimmune response J:134764
CNS inflammation J:134764
demyelination J:134764
hindlimb paralysis J:134764
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Trex1tm1Tld/Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:181257
normal mortality/aging J:181257
Rag2tm1.1Desi/Rag2tm1.1Desi
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		increased B cell derived lymphoma incidence J:168974
increased T cell derived lymphoma incidence J:168974
Rag2tm1.1Mss/Rag2tm1.1Mss
involves: 129S6/SvEvTac 		abnormal lymphopoiesis J:171970
abnormal pre-B cell morphology J:171970
decreased pre-B cell number J:171970
increased DN3 thymocyte number J:171970
normal neoplasm J:170462
Rag2tm1.1Mss/Rag2tm1.1Mss
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129S6/SvEvTac 		abnormal chromosome morphology J:170462
aneuploidy J:170462
increased lymphoma incidence J:170462
increased T cell derived lymphoma incidence J:170462
premature death J:170462
Rag2tm1Cgn/Rag2tm1Cgn
Xrcc4tm1Fwa/Xrcc4tm2Fwa
Tg(Cr2-cre)3Cgn/?
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal class switch recombination J:150339
spontaneous chromosome breakage J:150339
Rag2tm1Fwa/Rag2+
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag2tm1Fwa/Rag2+
Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag2tm1Fwa/Rag2tm1Fwa
Cd47tm1Fpl/Cd47tm1Fpl
Il2rgtm1Cgn/Y
involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		absent peripheral lymph nodes J:203904
decreased CD4-positive, alpha-beta T cell number J:203904
decreased lymphocyte cell number J:203904
decreased susceptibility to graft versus host disease J:203904
increased activated T cell number J:203904
increased CD8-positive, alpha-beta T cell number J:203904
increased susceptibility to Retroviridae infection J:203904
Rag2tm1Fwa/Rag2tm1Fwa
Rnaseh2atm1Crh/Rnaseh2atm1Crh
involves: 129S/SvEv 		perinatal lethality, complete penetrance J:232933
Rag2tm1Fwa/Rag2tm1Fwa
Rr299391tm1.1Fwa/Rr299391tm1.1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal T cell receptor delta chain V(D)J recombination J:149413
Rag2tm1Fwa/Rag2tm1Fwa
Sos1tm1.1Les/Sos1tm1.1Les
Tg(Lck-cre)1Cwi/0
involves: 129S/SvEv * C57BL/6 		abnormal T cell differentiation J:174536
decreased T cell proliferation J:174536
Rag2tm1Fwa/Rag2tm1Fwa
Stat1tm1Rds/Stat1tm1Rds
involves: 129S/SvEv * 129S6/SvEvTac 		increased gastrointestinal tumor incidence J:216040
increased mammary adenocarcinoma incidence J:216040
Rag2tm1Fwa/Rag2tm1Fwa
Tbatatm1Faf/Tbatatm1Faf
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal bone marrow cell physiology J:166065
abnormal T cell differentiation J:166065
increased thymocyte number J:166065
Rag2tm1Fwa/Rag2tm1Fwa
Tbx21tm1Glm/Tbx21tm1Glm
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal digestive system physiology J:141481
abnormal intestinal epithelium morphology J:141481
abnormal large intestine crypts of Lieberkuhn morphology J:141481
colitis J:141481
normal digestive/alimentary phenotype J:141481
increased tumor necrosis factor secretion J:141481
large intestinal inflammation J:141481
rectal prolapse J:141481
Rag2tm1Fwa/Rag2tm1Fwa
TcraLn3Jae/Tcra+
TcrbLn3Jae/Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased CD8-positive, alpha-beta T cell number J:143006
Rag2tm1Fwa/Rag2tm1Fwa
TcrbLn3Jae/Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased double-positive T cell number J:143006
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-NPM/ALK)N1Ingh/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster 		increased DN3 thymocyte number J:235890
increased T cell derived lymphoma incidence J:235890
increased thymus tumor incidence J:235890
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-NPM/ALK)N1Ingh/0
Tg(TcraTcrb)1100Mjb/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster 		increased gastrointestinal stromal tumor incidence J:235890
increased hepatocellular carcinoma incidence J:235890
increased sarcoma incidence J:235890
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0
involves: 129S/SvEv * BALB/c * C3H * C57BL/6 		normal immune system phenotype J:110446
Rag2tm1Fwa/Rag2tm1Fwa
Tg(EmuSR-tTa)83Bop/0
Tg(tetO-Nfatct1*)1Grc/0
involves: 129S/SvEv * C57BL/6J * CBA/J * FVB/N 		abnormal double-positive T cell morphology J:141917
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Igh-Pim1)1Brn/0
involves: 129S/SvEv * C57BL/6LiA * CBA 		decreased thymocyte number J:114561
Rag2tm1Fwa/Rag2tm1Fwa
Tg(KRT14-Il1f6)1Hblu/?
involves: 129S/SvEv * C57BL/6 * DBA/2 		abnormal skin morphology J:126327
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-Akt1*)M-1Pnt/0
involves: 129S/SvEv * C3H/He * C57BL/6 		absent CD4-positive, alpha-beta T cells J:135903
absent CD8-positive, alpha-beta T cells J:135903
increased double-positive T cell number J:135903
Rag2tm1Fwa/Rag2tm1Fwa
Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/?
Themis5AT161/Themis5AT161
involves: 129S/SvEv * C57BL/6 		arrested T cell differentiation J:151076
increased double-positive T cell number J:151076
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0
involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA/2 		abnormal CD4-positive T cell differentiation J:125548
abnormal positive T cell selection J:125548
decreased CD4-positive, alpha-beta T cell number J:125548
increased double-positive T cell number J:125548
thymus hyperplasia J:125548
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraCN.B1,TcrbCN.B1)SM1Jen/0
involves: 129S/SvEv * C57BL/6 		increased susceptibility to bacterial infection induced morbidity/mortality J:162539
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * C57BL/6J * DBA/2J 		abnormal CD8-positive, alpha beta T cell morphology J:125259
abnormal CD8-positive, alpha-beta T cell physiology J:125259
abnormal cytotoxic T cell physiology J:66565
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Themis5AT161/Themis5AT161
involves: 129S/SvEv * C57BL/6 * DBA/2 		decreased single-positive T cell number J:151076
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraTcrbNY8.3)1Pesa/0
NOD.Cg-Rag2tm1Fwa Tg(TcraTcrbNY8.3)1Pesa 		increased circulating glucose level J:94192
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0
involves: 129S/SvEv * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal double-positive T cell morphology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
abnormal thymus cell ratio J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0
Tg(TLK2mHEL)2Ccg/0
involves: 129S/SvEv * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
thyroid gland inflammation J:78309
Rag2tm1Fwa/Rag2tm1Fwa
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
Rag2tm1Fwa/Rag2tm1Fwa
Unc93b1tm1.1Kmiy/Unc93b1tm1.1Kmiy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		normal hematopoietic system phenotype J:174308
normal mortality/aging J:174308
Rag2tm1Fwa/Rag2tm1Fwa
Wdr1rede/Wdr1rede
involves: 129S/SvEv * C57BL/6 		abnormal immune system physiology J:134092
thrombocytopenia J:134092
Rag2tm2.1Desi/Rag2tm2.1Desi
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		increased T cell derived lymphoma incidence J:168974
Rr148tm1.1Fwa/Rr148tm1.1Fwa
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal B cell differentiation J:101400
Rr148tm1Fwa/Rr148tm1Fwa
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal B cell differentiation J:101400
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11/12/2024
MGI 6.24 		The Jackson Laboratory