Rap1a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rap1a
RAS-related protein 1a
MGI:97852

9 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rap1a^tm1Laaq/Rap1a^tm1Laaq B6.Cg-Rap1a^tm1Laaq	decreased angiogenesis	J:140236
Rap1a^tm1Laaq/Rap1a^tm1Laaq either: B6.Cg-Rap1a^tm1Laaq or (involves: C57BL/6)	abnormal leukocyte migration	J:140471
	abnormal macrophage physiology	J:140471
	abnormal neutrophil physiology	J:140471
	embryonic lethality, complete penetrance	J:140471
	normal immune system phenotype	J:140471
Rap1a^tm1Tze/Rap1a^tm1Tze involves: 129P2/OlaHsd * C57BL/6	abnormal leukocyte adhesion	J:144145
	decreased interleukin-2 secretion	J:144145
	decreased T cell proliferation	J:144145

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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