Rasa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasa1
RAS p21 protein activator 1
MGI:97860

31 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1⁺ C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J	abnormal behavior	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating phosphate level	J:211773
	increased heart weight	J:211773
	increased mean corpuscular hemoglobin	J:211773
	thrombocytopenia	J:211773
Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Rasa1^tm1Paw/Rasa1^tm1Paw either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal cell death	J:29825
	abnormal developmental patterning	J:29825
	abnormal embryonic tissue morphology	J:29825
	abnormal first pharyngeal arch morphology	J:29825
	abnormal rostral-caudal axis patterning	J:29825
	decreased embryo size	J:29825
	embryonic growth arrest	J:29825
	embryonic lethality during organogenesis, complete penetrance	J:29825
	excessive folding of visceral yolk sac	J:29825
	incomplete somite formation	J:29825
Rasa1^tm1Wid/Rasa1^tm1Wid involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6N	abnormal cardiovascular system physiology	J:189241
	decreased colon length	J:189241
	increased cardiomyocyte apoptosis	J:189241
	increased cellular sensitivity to ultraviolet irradiation	J:189241
	increased enterocyte apoptosis	J:189241
	increased sensitivity to induced cell death	J:189241
	increased susceptibility to induced colitis	J:189241
Rasa1^tm2.1Pdk/Rasa1^tm2.1Pdk involves: 129S6/SvEvTac * C57BL/6	abnormal blood vessel morphology	J:216433
	abnormal dorsal aorta morphology	J:216433
	abnormal intersomitic artery morphology	J:216433
	abnormal vitelline vasculature morphology	J:216433
	decreased embryo size	J:216433
	distended pericardium	J:216433
	embryonic lethality during organogenesis, complete penetrance	J:216433
	excessive folding of visceral yolk sac	J:216433

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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