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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ren1
renin 1 structural
MGI:97898
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Admtm1Unc/Adm+
Tg(Alb1-Ren)2Unc/?
129S6/SvEvTac-Admtm1Unc Tg(Alb1-Ren)2Unc 		cardiac hypertrophy J:125933
glomerulosclerosis J:125933
increased myocardial fiber size J:125933
increased systemic arterial blood pressure J:125933
renal cast J:125933
renal fibrosis J:125933
Gnastm3Lsw/Gnastm3Lsw
Ren1tm2(cre)Gom/Ren1+
involves: 129S6/SvEvTac * Black Swiss 		abnormal kidney physiology J:118076
abnormal renin activity J:118076
decreased circulating aldosterone level J:118076
decreased circulating renin level J:118076
decreased mean systemic arterial blood pressure J:118076
decreased renal glomerular filtration rate J:118076
decreased urine osmolality J:118076
increased urine prostaglandin level J:118076
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory