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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ret
ret proto-oncogene
MGI:97902
42 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Baxtm1Sjk/Baxtm1Sjk
Rettm1Heno/Rettm3.1(Bcl2l1)Heno
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129X1/SvJ * C57BL/6 * CBA 		abnormal enteric neuron morphology J:159854
Epha4Gt(PST038)Byg/Epha4Gt(PST038)Byg
Rettm1.1Kln/Rettm1.1Kln
involves: 129/Sv * BALB/c * C57BL/6 * CBA/J 		abnormal axon guidance J:110955
abnormal innervation pattern to muscle J:110955
Gfra1tm3Jmi/Gfra1tm3Jmi
Rettm14(Gfra1)Jmi/Ret+
involves: 129X1/SvJ 		no abnormal phenotype detected J:130616
Islr2tm1.1Ddg/Islr2tm1.1Ddg
Rettm1.1Ddg/Ret+
involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 		abnormal neuron morphology J:154926
Islr2tm1.1Ddg/Islr2tm1.1Ddg
Rettm1.1Ddg/Rettm1.1Ddg
involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 		abnormal neuron morphology J:154926
Kifbpem1Hmy/Kifbpem1Hmy
Rettm1Jmi/Ret+
involves: 129X1/SvJ 		abnormal embryo development J:253679
Kifbpem1Hmy/Kifbpem1Hmy
Rettm1Jmi/Rettm1Jmi
involves: 129X1/SvJ 		abnormal embryo development J:253679
Lhx1tm1Tmj/Lhx1+
Rettm1Kln/Rettm1Kln
Tg(Nes-cre)1Kln/0
involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL 		abnormal axon guidance J:110955
Lhx1tm1Tmj/Lhx1+
Rettm1.1Kln/Rettm1.1Kln
involves: 129/Sv * BALB/c * C57BL/6 * CBA/J 		abnormal axon guidance J:110955
Mrgprdtm1Mjz/?
Rettm1Ddg/Rettm1Ddg
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129 * 129S1/Sv * C57BL/6 * C57BL/6J * CBA/J 		abnormal neurite morphology J:126484
Pax2tm1Pgr/Pax2+
Rettm1Cos/Ret+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ 		absent kidney J:117753
absent ureter J:117753
decreased renal glomerulus number J:117753
impaired branching involved in ureteric bud morphogenesis J:117753
preweaning lethality, incomplete penetrance J:117753
renal hypoplasia J:117753
single kidney J:117753
Rettm1(RET)Vpa/Rettm1(RET)Vpa
involves: 129P2/OlaHsd 		no abnormal phenotype detected J:71588, J:102170
Rettm1(RET)Vpa/Rettm2(RET)Vpa
involves: 129P2/OlaHsd 		no abnormal phenotype detected J:71588
Rettm1Cos/Ret+
Wnt11tm1Amc/Wnt11+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1 		small kidney J:83430
Rettm1Cos/Ret+
Wnt11tm1Amc/Wnt11tm1Amc
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1 		impaired branching involved in ureteric bud morphogenesis J:83430
small kidney J:83430
Rettm1Cos/Rettm2(RET)Jmi
involves: 129S/Sv * C57BL/6 		aganglionic megacolon J:135153
Rettm1Cos/Rettm2(RET)Vpa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal kidney morphology J:71588
renal hypoplasia J:71588
Rettm1Heno/Rettm2(RET)Jmi
involves: 129X1/SvJ * C57BL/6 		abnormal defecation J:159854
abnormal enteric neural crest cell migration J:159854
abnormal feces composition J:159854
absent enteric neurons J:159854
decreased body weight J:159854
normal nervous system phenotype J:159854
postnatal growth retardation J:159854
postnatal lethality, incomplete penetrance J:159854
premature death J:159854
normal renal/urinary system phenotype J:159854
Rettm1Heno/Rettm3.1(Bcl2l1)Heno
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129X1/SvJ * C57BL/6 * CBA 		abnormal defecation J:159854
abnormal enteric neuron morphology J:159854
decreased body weight J:159854
decreased feces water content J:159854
Rettm2(RET)Heno/Rettm2(RET)Jmi
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S/Sv * C57BL/6 * CBA 		abnormal large intestine morphology J:135153
decreased neural crest cell number J:135153
Rettm2(RET)Heno/Rettm3.1(Bcl2l1)Heno
involves: 129/Sv * C57BL/6 		absent enteric neurons J:159854
absent kidney J:159854
Rettm2(RET)Jmi/Rettm2(RET)Jmi
involves: 129X1/SvJ * C57BL/6 		dilated ureter J:105047
hydronephrosis J:105047
Rettm2(RET)Jmi/Rettm2(RET)Jmi
Not Specified 		normal nervous system phenotype J:93262
Rettm2(RET)Jmi/Rettm3.1(Bcl2l1)Heno
involves: 129/Sv * C57BL/6 		abnormal enteric neural crest cell migration J:159854
absent enteric neurons J:159854
normal digestive/alimentary phenotype J:159854
normal mortality/aging J:159854
Rettm2(RET)Vpa/Rettm2(RET)Vpa
involves: 129P2/OlaHsd 		abnormal enteric ganglia morphology J:71588
abnormal enteric neural crest cell migration J:71588
abnormal kidney morphology J:71588
absent enteric neural crest cell J:71588
impaired branching involved in ureteric bud morphogenesis J:71588
kidney cyst J:71588
postnatal growth retardation J:71588
preweaning lethality, incomplete penetrance J:71588
renal hypoplasia J:71588
Rettm2(RET)Vpa/Rettm2(RET)Vpa
involves: 129P2/OlaHsd * C57BL/6J 		abnormal enteric ganglia morphology J:102170
small kidney J:102170
Rettm2.1Cos/?
Tg(Th-MYCN)41Waw/0
involves: 129S1/Sv * BALB/c * C57BL/6J 		increased neuroblastoma incidence J:261033
premature death J:261033
Rettm2.1Heno/Rettm2(RET)Jmi
involves: 129S/Sv * C57BL/6 * FVB/N 		abnormal enteric ganglia morphology J:135153
abnormal enteric neural crest cell migration J:135153
Rettm3(RET)Vpa/Rettm3(RET)Vpa
involves: 129P2/OlaHsd * C57BL/6J 		abnormal enteric ganglia morphology J:102170
abnormal intestinal peristalsis J:102170
abnormal kidney morphology J:102170
absent enteric neural crest cell J:102170
impaired branching involved in ureteric bud morphogenesis J:102170
neonatal lethality J:102170
renal hypoplasia J:102170
Rettm3.1(Bcl2l1)Heno/Ret+
involves: 129/Sv * C57BL/6 		decreased neuron apoptosis J:159854
normal digestive/alimentary phenotype J:159854
normal nervous system phenotype J:159854
Rettm4(RET)Vpa/Rettm4(RET)Vpa
either: 129S1/Sv-Rettm4(RET)Vpa or (involves: 129S1/Sv * C57BL/6J) 		no abnormal phenotype detected J:102170
Rettm5(RET)Jmi/Rettm5(RET)Jmi
involves: 129X1/SvJ * 129S1/Sv * C57BL/6 		no abnormal phenotype detected J:105047
Rettm5(RET)Vpa/Rettm5(RET)Vpa
either: 129S1/Sv-Rettm5(RET)Vpa or (involves: 129S1/Sv * C57BL/6J) 		abnormal enteric ganglia morphology J:102170
decreased renal glomerulus number J:102170
kidney cyst J:102170
small kidney J:102170
Rettm6(RET)Jmi/Rettm6(RET)Jmi
involves: 129X1/SvJ * 129S1/Sv * C57BL/6 		no abnormal phenotype detected J:105047
Rettm13.1Jmi/Rettm13Jmi
Slc6a3tm1(cre)Xz/Slc6a3+
involves: 129S1/Sv * 129X1/SvJ 		decreased locomotor activity J:114682
normal nervous system phenotype J:114682
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory