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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trim27
tripartite motif-containing 27
MGI:97904
13 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Trim27Gt(345D11)Cmhd/Trim27Gt(345D11)Cmhd
B6.129-Trim27Gt(345D11)Cmhd 		abnormal T-helper 1 physiology J:180433
abnormal T-helper 2 physiology J:180433
normal immune system phenotype J:180433
increased interferon-gamma secretion J:180433
increased tumor necrosis factor secretion J:180433
Trim27Gt(XP0484)Wtsi/Trim27Gt(XP0484)Wtsi
B6.129P2-Trim27Gt(XP0484)Wtsi 		decreased incidence of tumors by chemical induction J:189317
decreased tumor growth/size J:189317
early cellular replicative senescence J:189317
Trim27tm1Sis/Trim27tm1Sis
B6.Cg-Trim27tm1Sis 		decreased circulating alanine transaminase level J:206755
decreased circulating aspartate transaminase level J:206755
decreased hepatocyte apoptosis J:206755
decreased sensitivity to induced cell death J:206755
decreased susceptibility to induced morbidity/mortality J:206755
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory