Trim27 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trim27
tripartite motif-containing 27
MGI:97904

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Rb1^tm1Tyj/Rb1⁺ Trim27^{Gt(XP0484)Wtsi}/Trim27^{Gt(XP0484)Wtsi} involves: 129P2/OlaHsd * C57BL/6	increased pituitary gland tumor incidence	J:189317
	increased thyroid tumor incidence	J:189317
	increased tumor incidence	J:189317
Rb1^tm1Tyj/Rb1^tm1Tyj Trim27^{Gt(XP0484)Wtsi}/Trim27^{Gt(XP0484)Wtsi} involves: 129P2/OlaHsd * C57BL/6	increased cell proliferation	J:189317
Tg(KRT14-Esr1/HRAS)1Pkha/0 Trim27^{Gt(XP0484)Wtsi}/Trim27^{Gt(XP0484)Wtsi} involves: 129P2/OlaHsd * C57BL/6	early cellular replicative senescence	J:189317

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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