Rras Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rras
related RAS viral (r-ras) oncogene
MGI:98179

17 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rras^em1(IMPC)H/Rras^em1(IMPC)H C57BL/6N-Rras^em1(IMPC)H/H	decreased circulating calcium level	J:211773
	decreased fasting circulating glucose level	J:211773
	increased circulating serum albumin level	J:211773
	increased circulating triglyceride level	J:211773
	increased grip strength	J:211773
	prolonged QRS complex duration	J:211773
Rras^{Gt(OST24882)Lex}/Rras^{Gt(OST24882)Lex} B6;129S5-Rras^{Gt(OST24882)Lex}/Ieg	decreased B cell number	J:82809
	increased CD4-positive, alpha-beta T cell number	J:82809
	increased CD8-positive, alpha-beta T cell number	J:82809
Rras^{Gt(OST24882)Lex}/Rras^{Gt(OST24882)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal physiological neovascularization	J:104130
	abnormal tumor vascularization	J:104130
	abnormal vascular wound healing	J:104130
	artery stenosis	J:104130
Rras^tm1Itl/Rras⁺ involves: 129S6/SvEvTac * C57BL/6	increased tumor growth/size	J:181730
Rras^tm1Itl/Rras^tm1Itl either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6)	normal immune system phenotype	J:181730
Rras^tm1Itl/Rras^tm1Itl involves: 129S6/SvEvTac * C57BL/6	abnormal dendritic cell morphology	J:181730
	abnormal dendritic cell physiology	J:181730
	increased tumor growth/size	J:181730

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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