Rxrb Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rxrb
retinoid X receptor beta
MGI:98215

43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nr1h2^tm1.1Gstr/Nr1h2⁺ Rxrb^tm1Mma/Rxrb⁺ involves: 129 * C57BL/6	abnormal Sertoli cell morphology	J:101966
Rarb^tm1Vgi/Rarb^tm1Vgi Rxrb^tm1Rev/Rxrb^tm1Rev involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	abnormal excitatory postsynaptic potential	J:51892
	abnormal spatial learning	J:51892
	absent long-term depression	J:51892
	reduced long-term potentiation	J:51892
Rxra^tm1.1Pcn/Rxra^tm1.1Pcn Rxrb^tm1Ipc/Rxrb^tm1Ipc involves: 129S2/SvPas * C57BL/6 * SJL	normal embryo phenotype	J:146761
	embryonic growth retardation	J:146761
Rxra^tm1Ipc/Rxra^tm1Ipc Rxrb^tm1Mma/Rxrb^tm1Mma involves: 129S2/SvPas * C57BL/6	abnormal conotruncus septation	J:146761
	abnormal cornea stroma morphology	J:146761
	abnormal eye development	J:146761
	abnormal eyelid morphology	J:146761
	abnormal ocular fundus morphology	J:146761
	abnormal retina morphology	J:146761
	optic disk coloboma	J:146761
	ventral rotation of lens	J:146761
	ventricular myocardium compact layer hypoplasia	J:146761
Rxra^tm1Ipc/Rxra^tm4Ipc Rxrb^tm1Mma/Rxrb^tm1Pcn Tg(KRT14-cre)1Ipc/0 involves: 129S2/SvPas * C57BL/6 * SJL	abnormal epidermis stratum corneum morphology	J:109090
	abnormal keratinocyte morphology	J:109090
	abnormal skin condition	J:109090
	abnormal skin morphology	J:109090
Rxra^tm1Ipc/Rxra^tm4Ipc Rxrb^tm1Mma/Rxrb^tm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 involves: 129S2/SvPas	abnormal epidermis stratum corneum morphology	J:109090
	abnormal keratinocyte morphology	J:109090
	abnormal skin morphology	J:109090
	alopecia	J:102470
	dermal hyperplasia	J:102470
	epidermal hyperplasia	J:102470
	hair follicle degeneration	J:102470
	increased immunoglobulin level	J:102470
	mixed cellular infiltration to dermis	J:102470
Rxra^tm2Ipc/Rxra^tm2Ipc Rxrb^tm1Mma/Rxrb^tm1Mma involves: 129/Sv * C57BL/6	abnormal otic vesicle development	J:146761
	absent third pharyngeal arch artery	J:146761
	normal embryo phenotype	J:146761
	increased rhombomere 5 size	J:146761
	third pharyngeal arch hypoplasia	J:146761
Rxra^tm4Ipc/Rxra^tm4Ipc Rxrb^tm1Pcn/Rxrb^tm1Pcn Tg(KRT14-cre)1Ipc/0 involves: 129S2/SvPas * C57BL/6 * SJL	abnormal epidermis stratum corneum morphology	J:109090
	abnormal keratinocyte morphology	J:109090
	decreased cholesterol level	J:109090
	shiny skin	J:109090
Rxra^tm4Ipc/Rxra^tm4Ipc Rxrb^tm1Pcn/Rxrb^tm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 involves: 129S2/SvPas	alopecia	J:102470
	dermal cyst	J:102470
	dermatitis	J:102470
	dry skin	J:102470
	ear inflammation	J:102470
	enlarged cervical lymph nodes	J:102470
	enlarged liver	J:102470
	enlarged spleen	J:102470
	epidermal hyperplasia	J:102470
	hair follicle degeneration	J:102470
	increased leukocyte cell number	J:102470
	lymph node hyperplasia	J:102470
	mixed cellular infiltration to dermis	J:102470
	scaly skin	J:102470
	skin lesions	J:102470

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24