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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prrx2
paired related homeobox 2
MGI:98218
92 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Prrx1tm1Jfm/Prrx1tm1Jfm
Prrx2tm1Mjk/Prrx2tm1Mjk
involves: 129S4/SvJaeSor 		abnormal ameloblast morphology J:51596
abnormal ear position J:51596
abnormal limb morphology J:51596
abnormal mandible morphology J:51596
abnormal maxilla morphology J:51596
abnormal Meckel's cartilage morphology J:51596
abnormal tooth development J:51596
absent eyelids J:51596
absent incisors J:51596
aphagia J:51596
cleft palate J:51596
cyanosis J:51596
eyelids open at birth J:51596
growth retardation of incisors J:51596
neonatal lethality J:51596
respiratory distress J:51596
short mandible J:51596
small ears J:51596
Prrx1tm1Tex/Prrx1+
Prrx2tm1Hubr/Prrx2tm1Hubr
involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB 		abnormal stylohyoid ligament morphology J:50488
cleft secondary palate J:50488
distended abdomen J:50488
neonatal lethality, incomplete penetrance J:50488
palatal shelf hypoplasia J:50488
respiratory distress J:50488
Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Hubr/Prrx2+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB 		abnormal incisor morphology J:50488
abnormal mandible morphology J:50488
abnormal metacarpal bone morphology J:50488
short Meckel's cartilage J:50488
Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Hubr/Prrx2tm1Hubr
involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB 		abnormal cervical atlas morphology J:50488
abnormal cervical axis morphology J:50488
abnormal cranium morphology J:50488
abnormal digit morphology J:50488
abnormal forelimb morphology J:50488
abnormal forelimb zeugopod morphology J:50488
abnormal hindlimb zeugopod morphology J:50488
abnormal hyoid bone morphology J:50488
abnormal lumbar vertebrae morphology J:50488
abnormal malleus morphology J:50488
abnormal mandible morphology J:50488
abnormal metatarsal bone morphology J:50488
abnormal oval window morphology J:50488
abnormal scapular spine morphology J:50488
abnormal stapes morphology J:50488
abnormal stylohyoid ligament morphology J:50488
abnormal thoracic vertebrae morphology J:50488
abnormal tibia morphology J:50488
abnormal tongue position J:50488
abnormal ulna morphology J:50488
abnormal vertebral arch morphology J:50488
absent incisors J:50488
absent lateral semicircular canal J:50488
absent maxillary shelf J:50488
absent maxillary zygomatic process J:50488
absent Meckel's cartilage J:50488
absent pubic symphysis J:50488
absent temporal bone squamous part J:50488
absent vertebral arch J:50488
absent zygomatic arch J:50488
absent zygomatic bone J:50488
anotia J:50488
bowed radius J:50488
bowed ulna J:50488
cleft secondary palate J:50488
cyanosis J:50488
decreased width of hypertrophic chondrocyte zone J:50488
delayed bone ossification J:50488
ectopic cartilage J:50488
fused tarsal bones J:50488
micrognathia J:50488
neonatal lethality, complete penetrance J:50488
pointed snout J:50488
polydactyly J:50488
respiratory distress J:50488
short mandible J:50488
small otic capsule J:50488
spina bifida J:50488
xiphoid process foramen J:50488
Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Mjk/Prrx2+
involves: 129S7/SvEvBrd * C57BL/6 		abnormal hindlimb zeugopod morphology J:52212
abnormal incisor morphology J:51596
abnormal mandible morphology J:51596
forelimb oligodactyly J:52212
polydactyly J:52212
Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Mjk/Prrx2tm1Mjk
involves: 129S7/SvEvBrd 		abnormal aortic arch and aortic arch branch attachment J:60507
abnormal aortic arch morphology J:60507
abnormal artery morphology J:60507
abnormal fetal ductus arteriosus morphology J:60507
abnormal pulmonary trunk morphology J:60507
retroesophageal right subclavian artery J:60507
Prrx1tm1Tex/Prrx1tm1Tex
Prrx2tm1Mjk/Prrx2tm1Mjk
involves: 129S7/SvEvBrd * C57BL/6 		abnormal ameloblast differentiation J:51596
abnormal apical ectodermal ridge morphology J:52212
abnormal autopod morphology J:52212
abnormal bone ossification J:52212
abnormal carpal bone morphology J:52212
abnormal digit morphology J:52212
abnormal ear position J:51596
abnormal epiphyseal plate morphology J:52212
abnormal hindlimb zeugopod morphology J:52212
abnormal limb morphology J:51596
abnormal long bone hypertrophic chondrocyte zone J:52212
abnormal mandible morphology J:51596
abnormal odontoblast differentiation J:51596
abnormal phalanx morphology J:52212
abnormal tooth development J:51596
absent eyelids J:51596
absent incisors J:51596
absent maxillary shelf J:51596
absent maxillary zygomatic process J:51596
absent Meckel's cartilage J:51596
absent triquetrum J:52212
aphagia J:51596
cleft secondary palate J:51596
cyanosis J:51596
ectopic digits J:52212
eyelids open at birth J:51596
growth retardation of incisors J:51596
hindlimb oligodactyly J:52212
neonatal lethality, complete penetrance J:51596, J:52212
outer ear hypoplasia J:51596
postaxial polydactyly J:52212
preaxial polydactyly J:52212
respiratory distress J:51596
respiratory failure J:52212
short mandible J:51596
syndactyly J:52212
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory