Stmn2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stmn2
stathmin-like 2
MGI:98241

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chat^tm2(cre)Lowl/Chat⁺ Stmn2^em2Jmi/Stmn2^em2Jmi involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N	abnormal neuromuscular synapse morphology	J:337175
	abnormal neuron morphology	J:337175
	decreased grip strength	J:337175
	preweaning lethality, incomplete penetrance	J:337175
Stmn2^{em1(IMPC)Kmpc}/Stmn2⁺ C57BL/6NTac-Stmn2^{em1(IMPC)Kmpc}/Kmpc	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	increased circulating creatine kinase level	J:211773
	no spontaneous movement	J:211773
	unresponsive to tactile stimuli	J:211773
Stmn2^{em1(IMPC)Kmpc}/Stmn2^{em1(IMPC)Kmpc} C57BL/6NTac-Stmn2^{em1(IMPC)Kmpc}/Kmpc	no spontaneous movement	J:211773
	unresponsive to tactile stimuli	J:211773
Stmn2^em1Jmi/Stmn2⁺ C57BL/6N-Stmn2^em1Jmi	abnormal neuromuscular synapse morphology	J:337175
	abnormal neuron morphology	J:337175
	normal behavior/neurological phenotype	J:337175
	decreased grip strength	J:337175
	normal nervous system phenotype	J:337175
Stmn2^em1Jmi/Stmn2^em1Jmi C57BL/6N-Stmn2^em1Jmi	abnormal action potential	J:337175
	abnormal axon morphology	J:337175
	abnormal microtubule cytoskeleton morphology	J:337175
	abnormal mitochondrial shape	J:337175
	abnormal motor neuron innervation pattern	J:337175
	abnormal neurite morphology	J:337175
	abnormal neuromuscular synapse morphology	J:337175
	abnormal neuron morphology	J:337175
	abnormal phrenic nerve morphology	J:337175
	abnormal synaptic bouton morphology	J:337175
	abnormal synaptic vesicle number	J:337175
	normal behavior/neurological phenotype	J:337175
	decreased grip strength	J:337175
	delayed axon extension	J:337175
	impaired coordination	J:337175
	increased mechanical nociceptive threshold	J:337175
	infertility	J:337175
	normal nervous system phenotype	J:337175
	perinatal lethality, incomplete penetrance	J:337175
	preweaning lethality, incomplete penetrance	J:337175

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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