Epha4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Epha4
Eph receptor A4
MGI:98277

37 phenotypes from 14 alleles in 21 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Epha4^{Gt(PST038)Byg}/Epha4^{Gt(PST038)Byg} involves: 129P2/OlaHsd	abnormal innervation pattern to muscle	J:110955
Epha4^{Gt(PST038)Byg}/Epha4^{Gt(PST038)Byg} involves: 129P2/OlaHsd * C57BL/6J	abnormal anterior commissure morphology	J:67920
	abnormal axon guidance	J:67920, J:70273
	abnormal corticospinal tract morphology	J:67920
	abnormal gait	J:67920, J:70273
Epha4^{Gt(PST038)Byg}/Epha4^tm1Kldr involves: 129P2/OlaHsd	abnormal corticospinal tract morphology	J:82479
Epha4^{Gt(PST038)Byg}/Epha4^tm1Kldr involves: 129P2/OlaHsd	abnormal motor neuron innervation pattern	J:82479
Epha4^m1Btlr/Epha4^m1Btlr C57BL/6J-Epha4^m1Btlr	impaired limb coordination	J:156850
Epha4^rb-2J/Epha4^rb-2J C57BL/6J-Epha4^rb-2J/GrsrJ	abnormal gait	J:87289
	abnormal locomotor behavior	J:87289
	abnormal locomotor coordination	J:267074
	abnormal maternal nurturing	J:87289
	cryptorchism	J:87289
	decreased grip strength	J:87289
	decreased litter size	J:87289
	limb grasping	J:87289
	reduced male fertility	J:87289
Epha4^rb/Epha4^rb B6 x STOCK Epha4^rb/J	abnormal gait	J:87289
	cryptorchism	J:87289
	decreased grip strength	J:87289
	limb grasping	J:87289
	reduced male fertility	J:87289
Epha4^tm1.1Bzh/Epha4^tm1.1Bzh involves: 129S7/SvEvBrd * C57BL/6 * SJL	no abnormal phenotype detected	J:157159
Epha4^tm1.1Bzh/Epha4^tm1.1Bzh Isl1^tm1(cre)Sev/Isl1⁺ Tg(Hlxb9-GFP)1Tmj/0 involves: 129S/Sv * Black Swiss * C57BL/6J * CD-1 * FVB/N	abnormal abducens nerve morphology	J:243785
	abnormal innervation	J:243785
Epha4^tm1.1Bzh/Epha4^tm1.1Bzh Tg(Hlxb9-GFP)1Tmj/0 Twist2^tm1(cre)Dor/Twist2⁺ involves: 129S/Sv * C57BL/6J * CD-1 * FVB/N	abnormal innervation	J:243785
Epha4^tm1.1Bzh/Epha4^tm1.2Bzh Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * 129S7/SvEvBrd	abnormal corticospinal tract morphology	J:209606
	normal behavior/neurological phenotype	J:209606
Epha4^tm1.1Bzh/Epha4^tm1.2Bzh Tg(Hoxb8-cre)1403Uze/0 involves: 129S7/SvEvBrd * C57BL/6 * DBA/2	abnormal gait	J:209606
	abnormal spinal cord dorsal column morphology	J:209606
	abnormal spinal cord morphology	J:209606
Epha4^tm1.1Bzh/Epha4^tm1.2Bzh Tg(Slc17a6-icre)1Oki/0 involves: 129S7/SvEvBrd * C57BL/6	abnormal corticospinal tract morphology	J:209606
	abnormal gait	J:209606
	abnormal nerve fiber response	J:209606
	abnormal spinal cord dorsal column morphology	J:209606
	abnormal spinal cord morphology	J:209606
Epha4^tm1.2Bzh/Epha4^tm1.2Bzh involves: 129S7/SvEvBrd	abnormal gait	J:209606
	abnormal spinal cord dorsal column morphology	J:209606
	abnormal spinal cord morphology	J:209606
Epha4^tm1.2Bzh/Epha4^tm1.2Bzh involves: 129S7/SvEvBrd * C57BL/6 * FVB/N	abnormal gait	J:157159
Epha4^tm1.2Bzh/Epha4^tm1.2Bzh Tg(Hlxb9-GFP)1Tmj/0 involves: 129S/Sv * C57BL/6J * CD-1 * FVB/N	abnormal abducens nerve morphology	J:243785
	abnormal axon fasciculation	J:243785
	abnormal innervation	J:243785
	decreased motor neuron number	J:243785
Epha4^tm1Byd/Epha4⁺ involves: 129S1/Sv * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
Epha4^tm1Byd/Epha4^tm1Byd involves: 129S1/Sv * C57BL/6	abnormal anterior commissure morphology	J:67274
	abnormal anterior commissure pars anterior morphology	J:67274
	abnormal anterior commissure pars posterior morphology	J:67274
	abnormal barrel cortex morphology	J:115279
	abnormal corticospinal tract morphology	J:50573, J:67274
	abnormal gait	J:50573, J:67274
	abnormal innervation	J:50573, J:115279
	abnormal locomotor activation	J:50573
	abnormal placing response	J:50573
	abnormal primary somatosensory cortex morphology	J:115279
	abnormal spinal cord dorsal column morphology	J:50573
	absent anterior commissure	J:50573
	impaired limb coordination	J:50573
	normal nervous system phenotype	J:87398
	reduced long-term potentiation	J:87398
Epha4^tm1Bzh/Epha4^tm1Bzh involves: 129S7/SvEvBrd * C57BL/6	abnormal gait	J:157159
Epha4^tm1Kldr/Epha4^tm1Kldr involves: 129S/SvEv * C57BL/6	abnormal anterior commissure morphology	J:101019
	abnormal anterior commissure pars anterior morphology	J:101019
	abnormal anterior commissure pars posterior morphology	J:101019
	abnormal central pattern generator function	J:101019
	abnormal spinal cord dorsal column morphology	J:101019
	ectopic thalamus	J:101019
Epha4^tm1Kldr/Epha4^tm1Kldr Not Specified	abnormal central pattern generator function	J:82479
	abnormal corticospinal tract morphology	J:82479
	abnormal gait	J:82479
	abnormal motor neuron innervation pattern	J:82479
Epha4^tm1Pch/Epha4^tm1Pch involves: 129S2/SvPas * CD-1	abnormal axon morphology	J:150550
Epha4^tm1Pvan/Epha4^tm1Pvan involves: 129/Sv * C57BL/6	normal nervous system phenotype	J:115279
Epha4^tm2.1Kldr/Epha4^tm2.1Kldr involves: BALB/c * C57BL/6	abnormal miniature excitatory postsynaptic currents	J:154648
Epha4^tm2Kldr/Epha4^tm2.1Kldr Grik4^{tm1.1(cre)Slab}/Grik4⁺ involves: C57BL/6	normal nervous system phenotype	J:154648
Epha4^tm2Kldr/Epha4^tm2Kldr Tg(Pgk1-cre)1Lni/0 involves: BALB/c * C57BL/6	abnormal anterior commissure morphology	J:154648
	abnormal gait	J:154648
	abnormal spinal cord dorsal column morphology	J:154648
Epha4^tm5Kln/Epha4⁺ involves: 129/Sv * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
Epha4^tm5Kln/Epha4^tm5Kln involves: 129 * C57BL/6	abnormal corticospinal tract morphology	J:87398
	abnormal gait	J:87398
	normal nervous system phenotype	J:87398
Epha4^tm5Kln/Epha4^tm5Kln involves: 129/Sv * C57BL/6	abnormal barrel cortex morphology	J:115279
	abnormal innervation	J:115279
	abnormal primary somatosensory cortex morphology	J:115279
Epha4^tm5Kln/Epha4^tm5Kln involves: 129S/SvEv * C57BL/6	abnormal gait	J:101019
Epha4^tm5Kln/Epha4^tm5Kln involves: 129S/SvEv * C57BL/6	ectopic thalamus	J:101019

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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