About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sele
selectin, endothelial cell
MGI:98278
54 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Icam1tm1Bay/Icam1tm1Bay
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		decreased acute inflammation J:112286
impaired neutrophil chemotaxis J:112286
increased neutrophil cell number J:112286
normal integument phenotype J:112286
skin edema J:112286
Seletm1Hyn/Seletm1Hyn
Selltm1Hyn/Selltm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas 		abnormal common myeloid progenitor cell morphology J:31626
abnormal cytokine level J:31626
abnormal definitive hematopoiesis J:31626
abnormal erythropoiesis J:31626
abnormal granulocyte differentiation J:31626
abnormal myelopoiesis J:31626
extramedullary hematopoiesis J:31626
impaired hematopoiesis J:31626
impaired leukocyte tethering or rolling J:31626
impaired neutrophil recruitment J:31626
increased circulating interleukin-3 level J:31626
increased eosinophil cell number J:31626
increased erythroid progenitor cell number J:31626
increased leukocyte cell number J:31626
increased lymphocyte cell number J:31626
increased monocyte cell number J:31626
increased neutrophil cell number J:31626
increased spleen red pulp amount J:31626
increased spleen weight J:31626
increased susceptibility to bacterial infection J:31626
premature death J:31626
spleen hyperplasia J:31626
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm2Alb/Seletm2Alb
Selltm2Alb/Selltm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cellular extravasation J:70682
abnormal cervical lymph node morphology J:70682
abnormal liver physiology J:106550
abnormal lung morphology J:70682
abnormal lung vasculature morphology J:70682
abnormal spleen B cell follicle morphology J:70682
abnormal spleen B cell follicle shape J:106550
abnormal spleen morphology J:70682
decreased circulating alanine transaminase level J:106550
decreased spleen B cell follicle number J:106550
enlarged lymph nodes J:70682
extramedullary hematopoiesis J:70682
hepatic necrosis J:106550
normal immune system phenotype J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:70682, J:106550
normal integument phenotype J:70682
lung inflammation J:70682
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cytokine secretion J:70682
abnormal lung morphology J:70682
abnormal lung vasculature morphology J:70682
abnormal lymph node germinal center morphology J:70682
abnormal lymph node secondary follicle morphology J:70682
abnormal neutrophil physiology J:112286
abnormal spleen B cell follicle morphology J:70682
decreased acute inflammation J:112286
decreased spleen B cell follicle number J:70682
enlarged lymph nodes J:70682
extramedullary hematopoiesis J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:70682, J:112286
spontaneous skin ulceration J:70682, J:112286
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal leukocyte cell number J:101979
abnormal pilomotor reflex J:101979
decreased locomotor activity J:101979
eye inflammation J:101979
head tilt J:101979
increased neutrophil cell number J:101979
increased susceptibility to bacterial infection J:101979
spinning J:101979
tremors J:101979
weight loss J:101979
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory